Statins induce apoptosis in osteosarcoma cells by activation of Ampk and p38-MAPK via suppression of mevalonate pathway

被引：3
|
作者：
Kamel, Walied Abd-Elghani
Sugihara, Eiji
Yamaguchi, Sayaka Iwai
Nobusue, Hiroyuki
Maki, Kenta
Muto, Akihiro
Saya, Hideyuki
Shimizu, Takatsune
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-4182
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4182
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Licochalcone A-Induced Apoptosis Through the Activation of p38MAPK Pathway Mediated Mitochondrial Pathways of Apoptosis in Human Osteosarcoma Cells In Vitro and In Vivo
    Lin, Renn-Chia
    Yang, Shun-Fa
    Chiou, Hui-Ling
    Hsieh, Shu-Ching
    Wen, Shiua-Hua
    Lu, Ko-Hsiu
    Hsieh, Yi-Hsien
    CELLS, 2019, 8 (11)
  • [22] Ghrelin exhibited antidepressant and anxiolytic effect via the p38-MAPK signaling pathway in hippocampus
    Han, Qiu-Qin
    Huang, Hui-Jie
    Wang, Ya-Lin
    Yang, Liu
    Pilot, Adam
    Zhu, Xiao-Cang
    Yu, Rui
    Wang, Jing
    Chen, Xiao-Rong
    Liu, Qiong
    Li, Bing
    Wu, Gen-Cheng
    Yu, Jin
    PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2019, 93 : 11 - 20
  • [23] Hesperetin Induces Apoptosis in Human Glioblastoma Cells via p38 MAPK Activation
    Li, Qiang
    Miao, Ziwei
    Wang, Rui
    Yang, Jun
    Zhang, Dianbao
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2020, 72 (03): : 538 - 545
  • [24] Hypertrophic differentiation of mesenchymal stem cells is suppressed by xanthotoxin via the p38-MAPK/HDAC4 pathway
    Cao, Zhen
    Bai, Yun
    Liu, Chuan
    Dou, Ce
    Li, Jianmei
    Xiang, Junyu
    Zhao, Chunrong
    Xie, Zhao
    Xiang, Qiang
    Dong, Shiwu
    MOLECULAR MEDICINE REPORTS, 2017, 16 (03) : 2740 - 2746
  • [25] LDLs induce fibroblast spreading independently of the LDL receptor via activation of the p38 MAPK pathway
    Dobreva, I
    Waeber, G
    Mooser, V
    James, RW
    Widmann, C
    JOURNAL OF LIPID RESEARCH, 2003, 44 (12) : 2382 - 2390
  • [26] Epinephrine - Via activation of P38-Mapk - Abolishes the effect of aspirin on platelet deposition to collagen
    Mustonen, P
    van Willigen, G
    Lassila, R
    THROMBOSIS RESEARCH, 2001, 104 (06) : 439 - 449
  • [27] Xanthohumol induce apoptosis through p38 MAPK signaling pathway in human nasopharyngeal cancer cells
    Lo, M.
    Chen, D.
    LEUKEMIA RESEARCH, 2019, 85 : S70 - S70
  • [28] Advanced glycation end products stimulate human endothelial cells to produce MCP-1 via activation of p38-MAPK pathway.
    Hou, FF
    Guo, ZJ
    Liang, M
    Zhang, X
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 : 622A - 622A
  • [29] LncRNA FENDRR Upregulation Promotes Hepatic Carcinoma Cells Apoptosis By Targeting miR-362-5p Via NPR3 and p38-MAPK Pathway
    Qian, Guangyu
    Jin, Xiaoyan
    Zhang, Louwei
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2020, 35 (09) : 629 - 639
  • [30] Crotoxin induces apoptosis and autophagy in human lung carcinoma cells in vitro via activation of the p38 MAPK signaling pathway
    Han, Rong
    Liang, Hui
    Qin, Zheng-hong
    Liu, Chun-yu
    ACTA PHARMACOLOGICA SINICA, 2014, 35 (10) : 1323 - 1332
12345