One-pot assembly of 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines from pyrrolecarbo-nitriles and hydrazine

被引：1

作者：

Glotova, T. E. ^{[1
]}

Shabalin, D. A. ^{[1
]}

Dvorko, M. Yu. ^{[1
]}

Ushakov, I. A. ^{[1
]}

Schmidt, E. Yu. ^{[1
]}

Ivanov, A. V. ^{[1
]}

Mikhaleva, A. I. ^{[1
]}

Trofimov, B. A. ^{[1
]}

机构：

[1] Russian Acad Sci, Siberian Branch, AE Favorsky Irkutsk Inst Chem, Irkutsk 664033, Russia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2013年 / 49卷 / 04期

关键词：

3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines; hydrazine hydrate; 1H-pyrrole-2-carbonitriles; ANTIMICROBIAL ACTIVITY; DERIVATIVES; CHEMISTRY;

D O I：

10.1007/s10593-013-1282-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of pyrrole-2-carbonitriles with hydrazine hydrate in the presence of hydrazine dihydrochloride (ethylene glycol, 130-132A degrees D, 1-2 h, argon atmosphere) affords the hitherto unknown 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines in up to 86% yield.

引用

页码：561 / 565

页数：5

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