Synthesis of polyhydroquinoline derivatives under aqueous media

被引:40
作者
Bandgar, B. P. [1 ]
More, P. E. [1 ]
Kamble, V. T. [1 ]
Totre, J. V. [1 ]
机构
[1] Swami Ramanand Teerth Marathwada Univ, Organ Chem Res Lab, Sch Chem Sci, Vishnupuri 431606, Nanded, India
关键词
Dimedone; aldehydes; polyhydroquinoline; multi-component reactions; aqueous media;
D O I
10.3998/ark.5550190.0009.f01
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Highly efficient synthesis of polyhydroquinoline derivatives was reported via four component reaction of aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate in refluxing water. Excellent yields of the products and simple work-up are attractive features of this green protocol.
引用
收藏
页码:1 / 8
页数:8
相关论文
共 32 条
  • [21] Solar thermochemical reactions: four-component synthesis of polyhydroquinoline derivatives induced by solar thermal energy
    Mekheimer, Ramadan Ahmed
    Hameed, Afaf Abdel
    Sadek, Kamal Usef
    [J]. GREEN CHEMISTRY, 2008, 10 (05) : 592 - 593
  • [22] A Facile Synthesis of Polyhydroquinoline Derivatives via the Hantzsch Reaction Under Solvent Free-Conditions Using Potassium Dodecatungsto Cobaltate Trihydrate (K5CoW12O40•3H2O)
    Nagarapu, Lingaiah
    Apuri, Satyender
    Gaddam, Subhashini
    Bantu, Rajashaker
    Mahankhali, Venu C.
    Kantevari, Srinivas
    [J]. LETTERS IN ORGANIC CHEMISTRY, 2008, 5 (01) : 60 - 64
  • [23] Mild and eco-friendly chemoselective acylation of amines in aqueous medium
    Naik, S
    Bhattacharjya, G
    Kavala, VR
    Patel, BK
    [J]. ARKIVOC, 2004, : 55 - 63
  • [24] Chemoselective acylation of amines in aqueous media
    Naik, S
    Bhattacharjya, G
    Talukdar, B
    Patel, BK
    [J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2004, 2004 (06) : 1254 - 1260
  • [25] Chemical identification of binding sites for calcium channel antagonists
    Nakayama, H
    Kanaoka, Y
    [J]. HETEROCYCLES, 1996, 42 (02) : 901 - 909
  • [26] REDDY CS, 2008, CHINESE CHE IN PRESS
  • [27] A novel TMSI-mediated synthesis of Hantzsch 1,4-dihydropyridines at ambient temperature
    Sabitha, G
    Reddy, GSKK
    Reddy, CS
    Yadav, JS
    [J]. TETRAHEDRON LETTERS, 2003, 44 (21) : 4129 - 4131
  • [28] SAINANI JB, 1994, INDIAN J CHEM B, V33, P526
  • [29] SAUSINS A, 1988, HETEROCYCLES, V27, P269
  • [30] A new protocol to synthesize 1,4-dihydropyridines by using 3,4,5-trifluorobenzeneboronic acid as a catalyst in ionic liquid:: synthesis of novel 4-(3-carboxyl-1H-pyrazol-4-yl)-1,4-dihydropyridines
    Sridhar, R
    Perumal, PT
    [J]. TETRAHEDRON, 2005, 61 (09) : 2465 - 2470