Epistemological Approaches on Systemic and Synthetic Biology

被引:0
作者
Macovei, Olivia [1 ]
机构
[1] Stefan Cel Mare Univ Suceava, Doctoral Sch, Suceava, Romania
来源
BRAIN-BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE | 2022年 / 13卷 / 04期
关键词
systemic biology; synthetic biology; epistemology; KNOWLEDGE; NETWORK; DESIGN;
D O I
10.18662/brain/13.4/400
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The classical literature in the field of biology approaches the field of life from the perspective of the mechanisms by which the interactions between living systems are managed, while the systemic approach to biology emphasizes the interconnected networks of living nodes and the ways of communication of living systems, which is the very foundation of the idea of live as exchange of information on material or energetic support. More concretely, the emphasis on the informational dimension of biological interactions transfers the research object of synthetic biology from questions regarding the functionality of living systems, to those related to the ways of encoding information inside living structures that allow their configuration and reconfiguration in different evolutionary or constructive - in the case of synthetic biology - contexts. The analysis of the living system as a whole, from a structural-constructive perspective, takes from the systems theory a series of models for understanding the whole as something other than a simple aggregation of the component parts, emphasizing the integrity of the living system in a manner close to the systems approach in the science of complexity.
引用
收藏
页码:471 / 495
页数:25
相关论文
共 44 条
[1]  
Alon U., 2006, An Introduction to Systems Biology: Design Principles of Biological Circuits
[2]  
[Anonymous], 2002, LINKED EVERYTHING IS
[3]  
[Anonymous], ESSAYS BIOCHEM, V60, P337, DOI [10.1042/EBC20160024, DOI 10.1042/EBC20160024]
[4]   Synthetic biology [J].
Benner, SA ;
Sismour, AM .
NATURE REVIEWS GENETICS, 2005, 6 (07) :533-543
[5]   Mammalian Synthetic Biology: Engineering Biological Systems [J].
Black, Joshua B. ;
Perez-Pinera, Pablo ;
Gersbach, Charles A. .
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 19, 2017, 19 :249-277
[6]   Machine metaphors and ethics in synthetic biology [J].
Boldt, Joachim .
LIFE SCIENCES SOCIETY AND POLICY, 2018, 14
[7]   Putting the systems back into systems biology [J].
Cornish-Bowden, Athel .
PERSPECTIVES IN BIOLOGY AND MEDICINE, 2006, 49 (04) :475-489
[8]   The Explanatory Power of Network Models [J].
Craver, Carl F. .
PHILOSOPHY OF SCIENCE, 2016, 83 (05) :698-709
[9]   Piecing together a puzzle An exposition of synthetic biology [J].
Deplazes, Anna .
EMBO REPORTS, 2009, 10 (05) :428-432
[10]   ChromHMM: automating chromatin-state discovery and characterization [J].
Ernst, Jason ;
Kellis, Manolis .
NATURE METHODS, 2012, 9 (03) :215-216