Rotation between markers of systemic vascular inflammation and smoking in women

被引:284
作者
Bermudez, EA
Rifai, N
Buring, JE
Manson, JE
Ridker, PM
机构
[1] Brigham & Womens Hosp, Ctr Cardiovasc Dis Prevent, Div Prevent Med, Boston, MA 02215 USA
[2] Brigham & Womens Hosp, Div Cardiovasc, Boston, MA 02215 USA
[3] Leducq Ctr Cardiovasc Res, Boston, MA USA
[4] Childrens Hosp, Ctr Med, Boston, MA 02115 USA
[5] Harvard Univ, Sch Med, Boston, MA 02115 USA
关键词
D O I
10.1016/S0002-9149(02)02284-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We conducted an analysis among apparently healthy women enrolled in the Women's Health Study, to determine the relation between baseline high-sensitivity C-reactive protein, interleukin-6, soluble intercellular adhesion molecule type 1, P-selectin, and E-selectin with smoking status. We found that circulating levels of vascular inflammatory markers are independently related to smoking status in women, suggesting that smoking may promote atherothrombosis, at least in part, through vascular inflammation.
引用
收藏
页码:1117 / +
页数:4
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