Synthesis and in vitro anti-arthritic, anti-inflammatory studies on hypervalent pyranoside glycodendrimers with triazole bridging point

被引：4
作者：
Rajakumar, Perumal [1 ]
Anandhan, Ramasamy [1 ]
Kannan, Ayyavoo [1 ]
机构：
[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India
来源：
SUPRAMOLECULAR CHEMISTRY | 2013年 / 25卷 / 06期
关键词：
glycodendrimers; click chemistry; HRBC membrane; anti-arthritic; anti-inflammatory; PSEUDOMONAS-AERUGINOSA; RHEUMATOID-ARTHRITIS; PA-IIL; BINDING; DENDRIMERS; LECTIN; PROTEINS; DELIVERY; AGENTS; DRUGS;
D O I：
10.1080/10610278.2013.783917
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis of novel glycodendrimer scaffolds containing hypervalent sugar pyranosides and triazole bridging points is described. Dendrimers with a greater number of bridging triazole units and -d-glycopyranosyl surface groups exhibit better anti-arthritic and anti-inflammatory activity than dendrimers with less number of triazole and -d-glycopyranosyl units.
引用
收藏
页码：362 / 370
页数：9
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