Fast preparation of nano-hydroxyapatite/superhydrophilic reduced graphene oxide composites for bioactive applications

被引：63

作者：

Zanin, Hudson ^{[1
]}

Saito, Eduardo ^{[1
]}

Marciano, Fernanda Roberta ^{[2
]}

Ceragioli, Helder Jose ^{[3
]}

Campos Granato, Alessandro Eustaquio ^{[4
]}

Porcionatto, Marimelia ^{[4
]}

Lobo, Anderson Oliveira ^{[2
]}

机构：

[1] Natl Inst Space Res, Associated Lab Sensors & Mat, BR-12227010 Sao Jose Dos Campos, SP, Brazil

[2] Univ Vale do Paraiba, Inst Res & Dev, Lab Biomed Nanotechnol, BR-12244000 Sao Jose Dos Campos, SP, Brazil

[3] Univ Estadual Campinas, Dept Semicond Instrumentos & Foton, BR-13083852 Campinas, SP, Brazil

[4] Univ Fed Sao Paulo, Neurobiol Lab, BR-04039032 Sao Paulo, Brazil

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2013年 / 1卷 / 38期

基金：

巴西圣保罗研究基金会;

关键词：

CALCIUM-PHOSPHATE; ELECTROCHEMICAL PROCESSES; EXCITATION WAVELENGTH; RAMAN-SPECTRA; IN-VITRO; HYDROXYAPATITE; GROWTH; TITANIUM; NUCLEATION; DEPOSITION;

D O I：

10.1039/c3tb20550a

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

A method for the direct electrodeposition of globular nano-hydroxyapatite (nHAp) onto reduced graphene oxide (RGO) is presented and a model for the specific growth preference is discussed. Results show that the carboxyl (carboxylic acid)/carboxylate functional groups attached directly to the RGO after oxygen plasma treatment were essential to accelerate the OH- formation and the deposition of globular nHAp crystals. High resolution scanning electron microscopy, energy dispersive X-ray and X-ray diffraction showed that homogeneous, highly crystalline, stoichiometric nHAp crystals, with preferential growth in the (002) plane direction, were formed without any thermal treatment. The nHAp/RGO composites were shown to be an appropriate surface for mesenchymal stem cell adhesion with active formation of membrane projections.

引用

页码：4947 / 4955

页数：9

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