Effects of dairy intake on body weight and fat: a meta-analysis of randomized controlled trials

被引:216
作者
Chen, Mu [1 ]
Pan, An [1 ,5 ]
Malik, Vasanti S. [1 ]
Hu, Frank B. [1 ,2 ,3 ,4 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Boston, MA USA
[5] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117548, Singapore
关键词
POSTMENOPAUSAL CHINESE WOMEN; ENERGY-RESTRICTED DIET; CALCIUM SUPPLEMENTATION; MILK SUPPLEMENTATION; INCREASED CONSUMPTION; PRODUCT CONSUMPTION; YOUNG-WOMEN; LIFE-STYLE; LEAN MASS; OVERWEIGHT;
D O I
10.3945/ajcn.112.037119
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: Some intervention studies have suggested that dairy products may influence body weight, but the results remain controversial. Objective: We identified and quantified the effects of dairy consumption on body weight and fat mass from randomized controlled trials (RCTs). Design: We conducted a comprehensive search of PubMed and EMBASE databases (to April 2012) of English reports of RCTs regarding dairy consumption on body weight, body fat, or body weight and body fat in adults. The results across studies were pooled by using a random-effects meta-analysis. Results: Twenty-nine RCTs were included with a total of 2101 participants. Overall, consumption of dairy products did not result in a significant reduction in weight (-0.14 kg; 95% CI: -0.66, 0.38 kg; I-2 = 86.3%). In subgroup analysis, consumption of dairy products reduced body weight in the context of energy restriction or short-term intervention (<1 y) trials but had the opposite effect in ad libitum dietary interventions or long-term trials (>= 1 y). Twenty-two RCTs that reported results on body fat showed a modest reduction in the dairy group (-0.45 kg; 95% CI: -0.79, -0.11 kg; I-2 = 70.9%), and further stratified analysis indicated significant beneficial effects of dairy intervention on body fat in energy-restricted or short-term trials but not in long-term or ad libitum studies. Conclusions: This meta-analysis does not support the beneficial effect of increasing dairy consumption on body weight and fat loss in long-term studies or studies without energy restriction. However, dairy products may have modest benefits in facilitating weight loss in short-term or energy-restricted RCTs. Am J Clin Nutr 2012;96:735-47.
引用
收藏
页码:735 / 747
页数:13
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