Composition and Pharmacological Activity of Neutral Lipids from Rhizomes with Roots of the Introduced Plants Helleborus abchasicus and H-caucasicus

被引：1

作者：

Yunusova, S. G. ^{[1
]}

Sapozhnikova, T. A. ^{[1
]}

Khisamutdinova, R. Yu. ^{[1
]}

Makara, N. S. ^{[1
]}

Gabdrakhmanova, S. F. ^{[1
]}

Zarudii, F. S. ^{[1
]}

Ishchenko, Z. V. ^{[2
]}

Denisenko, O. N. ^{[2
]}

Lyashenko, S. S. ^{[2
]}

Yunusov, M. S. ^{[1
]}

机构：

[1] Russian Acad Sci, Ufa Inst Chem, 71 Prosp Oktyabrya, Ufa 450096, Russia

[2] Minist Hlth Russia, Volgograd State Med Univ Branch, Pyatigorsk Med Pharmaceut Inst, Pyatigorsk, Russia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2016年 / 52卷 / 06期

关键词：

Helleborus abchasicus; Helleborus caucasicus; Ranunculaceae; rhizomes with roots; lipids; fatty acids; anti-inflammatory activity; wound-healing activity;

D O I：

10.1007/s10600-016-1839-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The compositions of neutral lipids (NL) and fatty acids (FA) from subterranean parts of the introduced plants Helleborus abchasicus and H. caucasicus (Ranunculaceae) were established and compared with those of the wild species. The FA from diacyl- and triacylglycerides and free FA from these introduced species had elevated contents of unsaturated acids because of 18:2. The lipid-soluble NL constituents included 10 identified sterols, the major ones of which were cholesterol, sitosterol, and lanosterol. NL from H. abchasicus (introduced and wild) and H. caucasicus (wild) exhibited pronounced anti-inflammatory activity at the level of Voltaren and moderate wound-healing activity.

引用

页码：973 / 978

页数：6

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