Nanomolar and Selective Determination of Epinephrine in the Presence of Norepinephrine Using Carbon Paste Electrode Modified with Carbon Nanotubes and Novel 2-(4-Oxo-3-phenyl-3,4-dihydroquinazolinyl)-N′-phenyl-hydrazinecarbothioamide

被引：518

作者：

Beitollahi, Hadi ^{[1
]}

Karimi-Maleh, Hassan ^{[2
]}

Khabazzadeh, Hojatollah ^{[3
]}

机构：

[1] Yazd Univ, Fac Sci, Dept Chem, Yazd, Iran

[2] Isfahan Univ Technol, Coll Chem, Esfahan, Iran

[3] Shahid Bahonar Univ Kerman, Dept Chem, Kerman, Iran

来源：

ANALYTICAL CHEMISTRY | 2008年 / 80卷 / 24期

关键词：

D O I：

10.1021/ac801854j

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel modified carbon nanotube paste electrode of 2-(4oxo-3-phenyl-3,4-dihydro-quinazolinyl)-N'-phenyl-hydra-zinecarbothioamide (2PHC) was fabricated, and the electrooxidation of epinephrine (EP), norepinephrine (NE), and their mixture has been studied using electrochemical methods. The modified electrode displayed strong catalytic function for the oxidation of EP and NE and resolved the overlap voltammetric response of EP and NE into two well-defined voltammetric peaks of about 240 mV with square wave voltammetry (SWV). A linear response in the range of (5 x 10(-8))-(5.5 x 10(-4)) M with a detection limit (S/N = 3) of 9.4 nM for EP was obtained.

引用

页码：9848 / 9851

页数：4

共 24 条

[1] Novel 2,2′-[1,2-ethanediylbis(nitriloethylidyne)]-bis-hydroquinone double-wall carbon nanotube paste electrode for simultaneous determination of epinephrine, uric acid and folic acid [J].