Analysis of the Sox gene family in the European sea bass (Dicentrarchus labrax)

被引：27

作者：

Galay-Burgos, M

Llewellyn, L

Mylonas, CC

Canario, AV

Zanuy, S

Sweeney, GE

机构：

[1] Cardiff Univ, Sch Biosci, Cardiff, S Glam, Wales

[2] Inst Marine Biol Crete, Iraklion, Crete, Greece

[3] Univ Algarve, Ctr Ciencias Mar, Faro, Portugal

[4] CSIC, Inst Acuicultura Torre Sal, Castellon de La Plana, Spain

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 2004年 / 137卷 / 02期

关键词：

sea bass; gene family; Sox genes; PCR; sex determination; gene duplication;

D O I：

10.1016/j.cbpc.2003.12.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sox (SRY-related genes containing a HMG box) genes encode a family of transcription factors that are involved in a variety of developmental processes including sex determination. Twenty Sox genes are present in the genomes of humans and mice, but far less is known about the Sox gene family in other vertebrate types. We have obtained clones representing the HMG boxes of twelve Sox genes from European sea bass (Dicentrarchus labrax), a fish species whose farming is complicated by a heavily skewed sex ratio, with between 70% and 99% of offspring typically being male. The cloned Sox genes are members of the SoxB, SoxC, SoxE and SoxF groups. Sequence analysis shows that some of the clones represent genes duplicated in sea bass with respect to the mammalian Sox gene family. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：279 / 284

页数：6

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