Synthesis of sulfonamides and sulfonic esters via reaction of amines and phenols with thiols using H2O2-POCl3 system

被引：46
作者：
Bahrami, Kiumars [1 ,2 ]
Khodaei, Mohammad M. [1 ,2 ]
Abbasi, Jamshid [1 ]
机构：
[1] Razi Univ, Fac Chem, Dept Organ Chem, Kermanshah 6714967346, Iran
[2] Razi Univ, NNRC, Kermanshah 6714967346, Iran
来源：
TETRAHEDRON | 2012年 / 68卷 / 25期
关键词：
NUCLEOPHILIC-SUBSTITUTION REACTIONS; EXCHANGE-RESINS; SELECTIVE OXIDATION; ARYL; ANTICANCER; CONVERSION; SULFIDES; ACID; SULFONYLBENZOTRIAZOLES; SULFOXIDES;
D O I：
10.1016/j.tet.2012.04.040
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Phosphorus oxychloride efficiently promoted the synthesis of sulfonamides and sulfonic esters from thiols with hydrogen peroxide in the presence of Amberlite IRA-400 (OH-). This method has been applied to a variety of substrates including nucleophilic and sterically hindered amines, and also phenols with excellent yields of sulfonamides and sulfonic esters. In most cases these reactions are highly selective, simple, and clean, affording products in excellent yields and high purity. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5095 / 5101
页数：7
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