A Surface Coating that Rapidly Inactivates SARS-CoV-2

被引:169
|
作者
Behzadinasab, Saeed [3 ,4 ]
Chin, Alex [1 ]
Hosseini, Mohsen [3 ,4 ]
Poon, Leo [1 ,2 ]
Ducker, William A. [3 ,4 ]
机构
[1] Univ Hong Kong, LKS Fac Med, Sch Publ Hlth, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, LKS Fac Med, HKU Pasteur Res Pole, Hong Kong, Peoples R China
[3] Virginia Tech, Dept Chem Engn, Blacksburg, VA 24061 USA
[4] Virginia Tech, Ctr Soft Matter & Biol Phys, Blacksburg, VA 24061 USA
基金
美国国家科学基金会;
关键词
SARS-CoV-2; coronavirus; coating; Cu2O; cuprous oxide; virucidal; COVID-19; INFLUENZA-VIRUS;
D O I
10.1021/acsami.0c11425
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
SARS-CoV-2, the virus that causes the disease COVID-19, remains viable on solids for periods of up to 1 week, so one potential route for human infection is via exposure to an infectious dose from a solid. We have fabricated and tested a coating that is designed to reduce the longevity of SARS-CoV-2 on solids. The coating consists of cuprous oxide (Cu2O) particles bound with polyurethane. After 1 h on coated glass or stainless steel, the viral titer was reduced by about 99.9% on average compared to the uncoated sample. An advantage of a polyurethane-based coating is that polyurethane is already used to coat a large number of everyday objects. Our coating adheres well to glass and stainless steel as well as everyday items that people may fear to touch during a pandemic, such as a doorknob, a pen, and a credit card keypad button. The coating performs well in the cross-hatch durability test and remains intact and active after 13 days of being immersed in water or after exposure to multiple cycles of exposure to the virus and disinfection.
引用
收藏
页码:34723 / 34727
页数:5
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