Effect of HRD1 involved in endoplasmic reticulum-associated degradation (ERAD) on degradation of amyloid precursor protein (APP) and suppression of beta amyloid (Aβ) production

被引:0
|
作者
Kaneko, M
Koike, H
Murahashi, K
Omura, T
Okuma, Y
Nomura, Y
机构
[1] Chiba Inst Sci, Fac Pharmaceut Sci, Dept Pharmacol, Chiba 2880025, Japan
[2] Hokkaido Univ, Grad Sch Pharmaceut Sci, Dept Pharmacol, Sapporo, Hokkaido 0600812, Japan
[3] Hokkaido Univ, Grad Sch Med, Sapporo, Hokkaido 0608638, Japan
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:243P / 243P
页数:1
相关论文
共 50 条
  • [41] SEL1L-HRD1 ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION IS REQUIRED TO MAINTAIN PANCREATIC ISLET αLPHA CELL MASS AND FUNCTION
    Reinert, Rachel
    JOURNAL OF INVESTIGATIVE MEDICINE, 2022, 70 (07) : 1579 - 1579
  • [42] A Shared Endoplasmic Reticulum-associated Degradation Pathway Involving the EDEM1 Protein for Glycosylated and Nonglycosylated Proteins
    Shenkman, Marina
    Groisman, Bella
    Ron, Efrat
    Avezov, Edward
    Hendershot, Linda M.
    Lederkremer, Gerardo Z.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (04) : 2167 - 2178
  • [43] Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Saccharomyces cerevisiae APPLICATION OF A NOVEL ASSAY FOR GLYCOPROTEIN ERAD
    Hosomi, Akira
    Tanabe, Kaori
    Hirayama, Hiroto
    Kim, Ikjin
    Rao, Hai
    Suzuki, Tadashi
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (32) : 24324 - 24334
  • [44] The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR)
    Richie, Daryl L.
    Feng, Xizhi
    Hartl, Lukas
    Aimanianda, Vishukumar
    Krishnan, Karthik
    Powers-Fletcher, Margaret V.
    Watson, Douglas S.
    Galande, Amit K.
    White, Stephanie M.
    Willett, Taryn
    Latge, Jean-Paul
    Rhodes, Judith C.
    Askew, David S.
    VIRULENCE, 2011, 2 (01) : 12 - 21
  • [45] Arabidopsis OTU1, a linkage-specific deubiquitinase, is required for endoplasmic reticulum-associated protein degradation
    Zang, Yuepeng
    Gong, Yingya
    Wang, Qian
    Guo, Huiping
    Xiao, Wei
    PLANT JOURNAL, 2020, 101 (01): : 141 - 155
  • [46] A RING-H2 finger motif is essential for the function of Der3/Hrd1 in endoplasmic reticulum associated protein degradation in the yeast Saccharomyces cerevisiae
    Bordallo, J
    Wolf, DH
    FEBS LETTERS, 1999, 448 (2-3) : 244 - 248
  • [47] Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Regulates PC2 Function and Proglucagon Processing in Islet α-Cells
    Reinert, Rachel B.
    Zhu, Wenzhen
    Pan, Linxiu
    Russo, Anna Chiara
    Ray, Rohit
    Shrestha, Neha
    Lindberg, Iris
    Qi, Ling
    DIABETES, 2023, 72
  • [48] De3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins
    Bordallo, J
    Plemper, RK
    Finger, A
    Wolf, DH
    MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (01) : 209 - 222
  • [49] BECN1/Beclin 1 sorts cell-surface APP/amyloid precursor protein for lysosomal degradation
    Swaminathan, Gayathri
    Zhu, Wan
    Plowey, Edward D.
    AUTOPHAGY, 2016, 12 (12) : 2404 - 2419
  • [50] The VCP/p97 and YOD1 Proteins Have Different Substrate-dependent Activities in Endoplasmic Reticulum-associated Degradation (ERAD)
    Sasset, Linda
    Petris, Gianluca
    Cesaratto, Francesca
    Burrone, Oscar R.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (47) : 28175 - 28188