Label-free second harmonic and hyper Rayleigh scattering with high efficiency

被引:52
作者
Gomopoulos, Nikolaos [1 ]
Luetgebaucks, Cornelis [1 ]
Sun, Qinchao [1 ]
Macias-Romero, Carlos [1 ]
Roke, Sylvie [1 ]
机构
[1] Ecole Polytech Fed Lausanne, Sch Engn STI, Inst Bioengn IBI, Lab Fundamental BioPhoton LBP, CH-1015 Lausanne, Switzerland
基金
瑞士国家科学基金会; 欧洲研究理事会;
关键词
NONLINEAR-OPTICAL PROBE; LIGHT-SCATTERING; PARTICLE-SIZE; SURFACE; GENERATION; SPECTROSCOPY; ADSORPTION; INTERFACE; POLARIZATION;
D O I
10.1364/OE.21.000815
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We present a method to perform hyper Rayleigh scattering from aqueous solutions and second harmonic scattering measurements from unlabeled interfaces of liposomes and nanoparticles in dilute solutions. The water and interfacial response can be measured on a millisecond timescale, thus opening up the possibility to measure label-free time dependent transport processes in biological (membrane) systems. (C) 2013 Optical Society of America
引用
收藏
页码:815 / 821
页数:7
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