Label-free detection in biological applications of surface-enhanced Raman scattering

被引:104
作者
Han, Xiao Xia [1 ,2 ]
Zhao, Bing [3 ]
Ozaki, Yukihiro [1 ,2 ]
机构
[1] Kwansei Gakuin Univ, Sch Sci & Technol, Dept Chem, Sanda, Hyogo 6691337, Japan
[2] Kwansei Gakuin Univ, Sch Sci & Technol, Res Ctr Single Mol Vibrat, Sanda, Hyogo 6691337, Japan
[3] Jilin Univ, State Key Lab Supramol Struct & Mat, Changchun 130012, Peoples R China
关键词
Bacteria; Biorecognition; Cell; DNA; Estrogen; Label free; Metal nanoparticle; Protein; RNA; Surface-enhanced Raman scattering (SERS); HIGHLY SENSITIVE DETECTION; SINGLE-MOLECULE; DIFFRACTION LIMIT; CHEMICAL-ANALYSIS; SPECTROSCOPY; SILVER; PROTEIN; SERS; GLUTATHIONE; MECHANISMS;
D O I
10.1016/j.trac.2012.05.006
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Surface-enhanced Raman scattering (SERS) is currently undergoing rapid development as an ultra-sensitive analytical technique in the biological field. Label-free and extrinsic SERS labeling are two independent approaches that are commonly used to detect biomolecules directly and indirectly. The label-free detection method is a direct, convenient method for the detection of biomolecules and is more reliable than extrinsic SERS labeling, but its major limitations are poor selectivity in some complex mixtures and poor sensitivity at relatively low sample concentrations. However, label-free, highly sensitive, selective detection of biomolecules based on SERS is possible. With the development of novel SERS-active substrates, Raman instruments, and methods for sample pretreatment, the label-free protocol is becoming increasingly powerful and promising. This review highlights recent developments in label-free SERS-based techniques for bimolecular detection, including direct biomolecule identification, biomolecule ligand recognition via spectral differences among molecular bridges, and indirect phenolic molecule detection based on azo couplings. (c) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:67 / 78
页数:12
相关论文
共 87 条
[41]   A Study of Glutathione Molecules Adsorbed on Silver Surfaces Under Different Chemical Environments by Surface-Enhanced Raman Scattering in Combination with the Heat-Induced Sensing Method [J].
Huang, Genin Gary ;
Han, Xiao X. ;
Hossain, Mohammad Kamal ;
Kitahama, Yasutaka ;
Ozaki, Yukihiro .
APPLIED SPECTROSCOPY, 2010, 64 (10) :1100-1108
[42]   Development of a Heat-Induced Surface-Enhanced Raman Scattering Sensing Method for Rapid Detection of Glutathione in Aqueous Solutions [J].
Huang, Genin Gary ;
Han, Xiao X. ;
Hossain, Mohammad Kamal ;
Ozaki, Yukihiro .
ANALYTICAL CHEMISTRY, 2009, 81 (14) :5881-5888
[43]   Surface-enhanced Raman scattering for the rapid discrimination of bacteria [J].
Jarvis, RM ;
Brooker, A ;
Goodacre, R .
FARADAY DISCUSSIONS, 2006, 132 :281-292
[44]   Label-Free Detection of Proteins from Self-Assembled Protein-Silver Nanoparticle Structures using Surface-Enhanced Raman Scattering [J].
Kahraman, Mehmet ;
Sur, Ilknur ;
Culha, Mustafa .
ANALYTICAL CHEMISTRY, 2010, 82 (18) :7596-7602
[45]   Differential separation of protein mixtures using convective assembly and label-free detection with surface enhanced Raman scattering [J].
Keskin, Sercan ;
Kahraman, Mehmet ;
Culha, Mustafa .
CHEMICAL COMMUNICATIONS, 2011, 47 (12) :3424-3426
[46]  
Kitahama Y., 2011, SURFACE ENCHANCED RA, P285
[47]   Surface-Enhanced Raman Scattering-Based Label-Free Microarray Readout for the Detection of Microorganisms [J].
Knauer, Maria ;
Ivleva, Natalia P. ;
Liu, Xiangjiang ;
Niessner, Reinhard ;
Haisch, Christoph .
ANALYTICAL CHEMISTRY, 2010, 82 (07) :2766-2772
[48]  
Kneipp K, 2006, SURFACE ENHANCED RAM
[49]   Surface enhanced Raman scattering spectroscopy of Ag nanoparticle aggregates directly photo-reduced on pathogenic bacterium (Helicobacter pylori) [J].
Kudo, Hayato ;
Itoh, Tamitake ;
Kashiwagi, Takehiro ;
Ishikawa, Mitsuru ;
Takeuchi, Hiroaki ;
Ukeda, Hiroyuki .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2011, 221 (2-3) :181-186
[50]   Surface-enhanced Raman scattering studies of human transcriptional coactivator p300 [J].
Kumar, G. V. Pavan ;
Reddy, B. A. Ashok ;
Arif, Mohammed ;
Kundu, Tapas K. ;
Narayana, Chandrabhas .
JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (33) :16787-16792