Lanostane triterpenoids from Ganoderma hainanense J. D. Zhao

被引：31

作者：

Peng, XingRong ^{[1
,2
]}

Liu, JieQing ^{[1
]}

Xia, JianJun ^{[1
]}

Wang, CuiFang ^{[1
]}

Li, XuYang ^{[1
,2
]}

Deng, YuanYuan ^{[1
,2
]}

Bao, NiMan ^{[1
,2
]}

Zhang, ZhiRun ^{[1
]}

Qiu, MingHua ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China

来源：

PHYTOCHEMISTRY | 2015年 / 114卷

关键词：

Ganoderma hainanense; Lanostane triterpenoids; X-ray diffraction; Mosher's method; Cytotoxicity; GANOLUCIDIC ACID; FRUITING BODY; LUCIDUM; CONSTITUENTS; TERPENOIDS; CYTOTOXICITY; SINENSE; SPORES; CELLS;

D O I：

10.1016/j.phytochem.2014.10.009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chemical investigation of the fruiting bodies of Ganoderma hainanense resulted in isolation of fourteen lanostane triterpenoids, including nine ganoderma acids and five ganoderma alcohols, together with five known compounds. Structural elucidation was determined using extensive spectroscopic technologies, Mosher's method and X-ray single crystal diffraction. Three of the compounds showed inhibitory activities against HL-60, SMMC-7721, A-549 and MCF-7 cells with IC50 values of 15.0-40.0 mu M. (C) 2014 Elsevier Ltd. All rights reserved.

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收藏

页码：137 / 145

页数：9

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