Studies towards 1,3-diol units starting from syn β-hydroxy acylsilanes

被引：4

作者：

Reddy, Gangireddy PavanKumar ^{[1
]}

Murthy, Akondi Srirama ^{[1
,2
]}

Reddy, J. Satyanarayana ^{[1
,2
]}

Das, Saibal ^{[2
]}

Roisnel, Thierry ^{[1
]}

Yadav, Jhillu S. ^{[2
]}

Chandrasekhar, Srivari ^{[2
]}

Gree, Rene ^{[1
]}

机构：

[1] Univ Rennes 1, Inst Sci Chim Rennes, CNRS UMR 6226, F-35042 Rennes, France

[2] Indian Inst Chem Technol, CSIR, Nat Prod Chem Div, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 02期

关键词：

Acyl silanes; 1,3 Diols; Aldol; Silicon; Tischenko; ALDOL-TISHCHENKO REACTION; DIASTEREOFACIAL SELECTIVITY; SYNTHETIC EQUIVALENTS; REAGENTS; REARRANGEMENTS; ALDEHYDES; ADDITIONS; SILICON; CATION;

D O I：

10.1016/j.tetlet.2013.11.034

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three complementary strategies have been explored to obtain stereodefined 1,3 diols starting from easily accessible syn beta-hydroxy acylsilanes: fluoride induced migrations of substituents on silicon, a Grignard addition followed by protodesilylation and Tischenko-type reactions. Preliminary data on scope and limitations of these processes are presented. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：365 / 368

页数：4

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