Prescription of high-potency corticosteroid agents and clotrimazole-betamethasone dipropionate by pediatricians

被引:19
作者
Fleischer, AB [1 ]
Feldman, SR [1 ]
机构
[1] Wake Forest Univ, Sch Med, Dept Dermatol, Winston Salem, NC 27157 USA
关键词
topical corticosteroid; clotrimazole-betamethasone dipropionate; antifungal agent; dermatitis; fungal infection; pediatrics;
D O I
10.1016/S0149-2918(99)80051-4
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Family physicians, internists, and pediatricians are more likely to prescribe combination topical antifungal-topical corticosteroid preparations than are dermatologists. One such preparation, clotrimazole-betamethasone dipropionate, can cause atrophy because it has a high-potency corticosteroid component. We analyzed data from the National Ambulatory Medical Care Survey for visits to pediatricians from 1990 to 1994 and isolated visits at which a topical corticosteroid agent or clotrimazole-betamethasone dipropionate was prescribed. Pediatricians rarely prescribed single-agent, high-potency topical corticosteroid agents in managing patients with skin disorders. High-potency corticosteroid agents accounted for 5.0% of topical corticosteroid prescriptions, whereas 56.3% were low-potency and 38.7% were medium-potency agents. Of the 696,285 mentions of clotrimazole-betamethasone dipropionate, 56.4% (389,920) were for children aged newborn to 4 years; diagnoses were erythematodesquamatous dermatoses, diaper rash, tinea, well-baby visit, and candidiasis. In contrast, for dermatologists nationwide, no drug mention existed for this combination agent for children aged newborn to 4 years over the 5-year study period. Our results show that clotrimazole-betamethasone dipropionate is prescribed inappropriately by pediatricians, especially in the treatment of young children. Pediatricians rarely use high-potency topical corticosteroid agents, but most of their use of clotrimazole-betamethasone dipropionate is in the youngest children, in whom such corticosteroid use is least appropriate. This prescription pattern suggests that some pediatricians may be unaware that clotrimazole-betamethasone dipropionate has a high-potency corticosteroid component.
引用
收藏
页码:1725 / 1731
页数:7
相关论文
共 17 条
[1]   Treatment of diaper dermatitis [J].
Boiko, S .
DERMATOLOGIC CLINICS, 1999, 17 (01) :235-+
[2]   DOES NAFTIFINE HAVE ANTIINFLAMMATORY PROPERTIES - A DOUBLE-BLIND COMPARATIVE-STUDY WITH 1-PERCENT CLOTRIMAZOLE 1-PERCENT HYDROCORTISONE IN CLINICALLY DIAGNOSED FUNGAL INFECTION OF THE SKIN [J].
EVANS, EGV ;
JAMES, IGV ;
SEAMAN, RAJ ;
RICHARDSON, MD .
BRITISH JOURNAL OF DERMATOLOGY, 1993, 129 (04) :437-442
[3]  
FLEISCHER AB, 1993, SCHOCH LETT, V43, P11
[4]   TOPICAL CORTICOSTEROIDS FOR SKIN DISORDERS IN INFANTS AND CHILDREN [J].
HARPER, J .
DRUGS, 1988, 36 :34-37
[5]  
Jethwa K, 1994, Prof Care Mother Child, V4, P219
[6]  
KATZ HI, 1984, CUTIS, V34, P183
[7]   DERMATOLOGICAL SERVICES PROVIDED TO CHILDREN AND ADOLESCENTS BY PRIMARY-CARE AND OTHER PHYSICIANS IN THE UNITED-STATES [J].
KROWCHUK, DP ;
BRADHAM, DD ;
FLEISCHER, AB .
PEDIATRIC DERMATOLOGY, 1994, 11 (03) :199-203
[8]  
*MED EC CO INC, 1997, PHYS DESK REF, P2515
[9]   NAFTIFINE CREAM 1-PERCENT VERSUS ECONAZOLE CREAM 1-PERCENT IN THE TREATMENT OF TINEA CRURIS AND TINEA CORPORIS [J].
MILLIKAN, LE ;
GALEN, WK ;
GEWIRTZMAN, GB ;
HORWITZ, SN ;
LANDOW, RK ;
NESBITT, LT ;
ROTH, HL ;
SEFTON, J ;
DAY, RM .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1988, 18 (01) :52-56
[10]  
*NAT AMB MED CAR S, REL SE DOC