Daytime sleepiness, sleep disturbance and functioning impairment in bipolar disorder

被引:14
作者
Walz, Julio C. [1 ,2 ,3 ]
Magalhaes, Pedro V. [1 ,2 ,3 ]
Reckziegel, Ramiro [1 ,2 ]
Costanzi, Monise [1 ,2 ]
Giglio, Larriany [1 ,2 ]
Kapczinski, Flavio [1 ,2 ]
机构
[1] Univ Fed Rio Grande do Sul, Bipolar Disorders Program, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil
[2] Univ Fed Rio Grande do Sul, INCT Translat Med, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil
[3] Ctr Univ La Salle Canoas, Canoas, Brazil
关键词
bipolar disorder; disability; functioning; sleep disorders; sleepiness; DEPRESSION; SCALE;
D O I
10.1111/j.1601-5215.2012.00673.x
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Objective: To verify the prevalence and clinical impact of excessive daytime sleepiness (EDS) in outpatients with bipolar disorder. Methods: Eighty-one outpatients with bipolar disorder and 79 healthy control subjects were recruited. Patients were required not to be acutely manic or depressed. We used the Epworth Sleepiness Scale, the Pittsburgh Sleep Quality Index and the Functioning Assessment Short Test to assess sleepiness, sleep problems and functioning, respectively. Results: Patients had a higher prevalence of sleepiness (40%) than the control group (18%). Sleepiness and sleep disturbance had independent impacts on disability in the multivariable model. Conclusions: This study suggests that EDS is a relevant clinical dimension in patients with bipolar disorder. It is a frequent symptom that often overlaps with other sleep disturbances. This study also reveals that once present it has the potential to increase functional impairment.
引用
收藏
页码:101 / 104
页数:4
相关论文
共 21 条
[1]   Alternatives for logistic regression in cross-sectional studies: An empirical comparison of models that directly estimate the prevalence ratio [J].
Aluísio JD Barros ;
Vânia N Hirakata .
BMC Medical Research Methodology, 3 (1) :1-13
[2]   Portuguese-language version of the Epworth sleepiness scale: validation for use in Brazil [J].
Bertolazi, Alessandra Naimaier ;
Fagondes, Simone Chaves ;
Hoff, Leonardo Santos ;
Pedro, Vinicius Dallagasperina ;
Menna Barreto, Sergio Saldanha ;
Johns, Murray W. .
JORNAL BRASILEIRO DE PNEUMOLOGIA, 2009, 35 (09) :877-883
[3]   THE PITTSBURGH SLEEP QUALITY INDEX - A NEW INSTRUMENT FOR PSYCHIATRIC PRACTICE AND RESEARCH [J].
BUYSSE, DJ ;
REYNOLDS, CF ;
MONK, TH ;
BERMAN, SR ;
KUPFER, DJ .
PSYCHIATRY RESEARCH, 1989, 28 (02) :193-213
[4]   Bipolar disorder and age-related functional impairment [J].
Cacilhas, Alice Aita ;
da Silva Magalhaes, Pedro Vieira ;
Cereser, Keila Maria ;
Walz, Julio Cesar ;
Weyne, Fernanda ;
Rosa, Adriane Ribeiro ;
Vieta, Eduard ;
Kapczinski, Flavio .
REVISTA BRASILEIRA DE PSIQUIATRIA, 2009, 31 (04) :354-357
[5]   Validity of a Short Functioning Test (FAST) in Brazilian Outpatients with Bipolar Disorder [J].
Cacilhas, Alice Aita ;
da Silva Magalhaes, Pedro Vieira ;
Cereser, Keila Maria ;
Walz, Julio Cesar ;
Weyne, Fernanda ;
Ribeiro Rosa, Adriane ;
Vieta, Eduard ;
Kapczinski, Flavio .
VALUE IN HEALTH, 2009, 12 (04) :624-627
[6]   Adjunctive Armodafinil for Major Depressive Episodes Associated With Bipolar I Disorder: A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Proof-of-Concept Study [J].
Calabrese, Joseph R. ;
Ketter, Terence A. ;
Youakim, James M. ;
Tiller, Jane M. ;
Yang, Ronghua ;
Frye, Mark A. .
JOURNAL OF CLINICAL PSYCHIATRY, 2010, 71 (10) :1363-1370
[7]   Chronobiology, excessive daytime sleepiness and depression: Is there a link? [J].
Chellappa, Sarah Laxhmi ;
Schroeder, Carmen ;
Cajochen, Christian .
SLEEP MEDICINE, 2009, 10 (05) :505-514
[8]  
Dauvilliers Yves, 2005, Dialogues Clin Neurosci, V7, P347
[9]   Effect of sleep apnea on cognition and mood [J].
El-Ad, B ;
Lavie, P .
INTERNATIONAL REVIEW OF PSYCHIATRY, 2005, 17 (04) :277-282
[10]   Circadian preference in bipolar disorder [J].
Falsin Giglio, Larriany Maria ;
Magalhaes, Pedro V. S. ;
Andersen, Monica Levy ;
Walz, Julio Cesar ;
Jakobson, Lourenco ;
Kapczinski, Flavio .
SLEEP AND BREATHING, 2010, 14 (02) :153-155