An efficient synthesis of new C-2 aryl substituted quinolines based on three component imino Diels-Alder reaction

被引：38

作者：

Kouznetsov, VV ^{[1
]}

Bohórquez, ARR

Saavedra, LA

Medina, RF

机构：

[1] Univ Ind Santander, Escuela Quim, Lab Quim Organ & Biomol, Bucaramanga, Colombia

[2] Univ Talca, Inst Quim Recursos Nat, Talca, Chile

[3] Univ Nacl Colombia, Dept Quim, Lab Sintesis Organ & Organomet, Bogota, Colombia

来源：

MOLECULAR DIVERSITY | 2006年 / 10卷 / 01期

关键词：

C-2 substituted quinolines; three component imino Diels-Alder reaction;

D O I：

10.1007/s11030-006-2344-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New effective approach to the synthesis of a wide variety of C-2 nitro or aminophertyl substituted quinolines was reported using diverse intermediate 4-(2-oxopyrrolinidyl-l)-tetrahydroquinolines that were prepared by a three component imino Diels-Alder reaction was reported. The key aromatisation process occurs cleanly with the loss of the 2-oxopyrrolinidyl-1 fragment.

引用

页码：29 / 37

页数：9

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