The close interrelation between colorectal cancer, infection and microbiota

被引:6
作者
Massaut, Edouard [1 ]
Hendlisz, Barbara [2 ]
Klastersky, Jean A. [2 ]
机构
[1] Ctr Hosp Luxembourg, Serv Chirurg, Rue Barble 4, L-1210 Luxembourg, Luxembourg
[2] Univ Libre Bruxelles, Inst Jules Bordet, Serv Oncol Med, Brussels, Belgium
关键词
cancer genesis; colorectal cancer; infection; occult cancer; postoperative complications; HELICOBACTER-PYLORI INFECTION; SURGICAL SITE INFECTIONS; FUSOBACTERIUM-NUCLEATUM; COLON-CANCER; RISK-FACTOR; INFLAMMATION; RECURRENCE; RESECTION; ABSCESS;
D O I
10.1097/CCO.0000000000000543
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose of review Evaluate the recent literature about the relation of clinical infection and colorectal cancer in terms of diagnosis of an occult infection and possible impact on oncological outcome and review the possible role of the gut microbiota in the role of colorectal cancer oncogenesis. Recent findings Data published within the 2 last years have been reviewed and the conclusions, mostly supporting previously published information, have been critically discussed. Summary Infection (bacteremia, cellulitis) might be a surrogate of occult colorectal cancer and postoperative infection complications might jeopardize long-term survival after potentially curative surgery. The role of the gut microbiota in the genesis of colorectal cancer remains an exciting though unresolved question.
引用
收藏
页码:362 / 367
页数:6
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