Oncologic outcomes after nipple-sparing mastectomy: A single-institution experience

被引:27
作者
Frey, Jordan D. [1 ]
Alperovich, Michael [1 ]
Kim, Jennifer Chun [2 ]
Axelrod, Deborah M. [2 ]
Shapiro, Richard L. [2 ]
Choi, Mihye [1 ]
Schnabel, Freya R. [2 ]
Karp, Nolan S. [1 ]
Guth, Amber A. [2 ]
机构
[1] NYU, Langone Med Ctr, Dept Plast Surg, 550 First Ave, New York, NY 10016 USA
[2] NYU, Langone Med Ctr, Dept Surg, New York, NY 10016 USA
关键词
nipple-sparing mastectomy; breast cancer; outcomes; locoregional recurrence; oncologic; reconstructive; BREAST-CANCER PATIENTS; RECURRENCE; SKIN; SAFETY; RISK;
D O I
10.1002/jso.24097
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
IntroductionLong-term oncologic outcomes in nipple-sparing mastectomy (NSM) continue to be defined. Rates of locoregional recurrence for skin-sparing mastectomy (SSM) and NSM in the literature range from 0% to 14.3%. We investigated the outcomes of NSM at our institution. MethodsPatients undergoing NSM at our institution from 2006 to 2014 were identified and outcomes were analyzed. ResultsFrom 2006 to 2014, 319 patients (555 breasts) underwent NSM. One-hundered and fourty-one patients (237 breasts) had long-term follow-up available. Average patient age and BMI were 47.78 and 24.63. Eighty-four percent of patients underwent mastectomy primarily for a therapeutic indication. Average tumor size was 1.50cm with the most common histologic type being invasive ductal carcinoma (62.7%) followed by DCIS (23.7%). Average patient follow-up was 30.73 months. There was one (0.8%) incidence of ipsilateral chest-wall recurrence. There were 0.37 complications per patient. ConclusionsWe examined our institutional outcomes with NSM and found a locoregional recurrence rate of 0.8% with no nipple-areolar complex recurrence. This rate is lower than published rates for both NSM and SSM. J. Surg. Oncol. 2016;113:8-11. (c) 2015 Wiley Periodicals, Inc.
引用
收藏
页码:8 / 11
页数:4
相关论文
共 17 条
[11]   Breast cancer recurrence after nipple-sparing mastectomy: one institution's experience [J].
Poruk, Katherine E. ;
Ying, Jian ;
Chidester, Jeremy R. ;
Olson, Joshua R. ;
Matsen, Cindy B. ;
Neumayer, Leigh ;
Agarwal, Jayant .
AMERICAN JOURNAL OF SURGERY, 2015, 209 (01) :212-217
[12]  
Sakorafas George H, 2008, AORN J, V88, P605, DOI 10.1016/j.aorn.2008.06.001
[13]   Comparison of oncological safety between nipple sparing mastectomy and total mastectomy using propensity score matching [J].
Seki, T. ;
Jinno, H. ;
Okabayashi, K. ;
Murata, T. ;
Matsumoto, A. ;
Takahashi, M. ;
Hayashida, T. ;
Kitagawa, Y. .
ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 2015, 97 (04) :291-297
[14]   The Risk Factors Influencing between the Early and Late Recurrence in Systemic Recurrent Breast Cancer [J].
Song, Won Jong ;
Kim, Kwan Il ;
Park, Sang Hyun ;
Kwon, Mi Seon ;
Lee, Tae Hoon ;
Park, Heung Kyu ;
An, Jung Suk .
JOURNAL OF BREAST CANCER, 2012, 15 (02) :218-223
[15]   Evaluating Long-Term Outcomes following Nipple-Sparing Mastectomy and Reconstruction in the Irradiated Breast [J].
Spear, Scott L. ;
Shuck, John ;
Hannan, Lindsay ;
Albino, Frank ;
Patel, Ketan M. .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2014, 133 (05) :605E-614E
[16]   Skin and Nipple-Areola Complex Sparing Mastectomy in Breast Cancer Patients 15-Year Experience [J].
Stanec, Zdenko ;
Zic, Rado ;
Budi, Srecko ;
Stanec, Sanda ;
Milanovic, Rudolf ;
Vlajcic, Zlatko ;
Roje, Zeljka ;
Rudman, Franjo ;
Martic, Kresimir ;
Held, Rebeka ;
Bozo, Gorjanc .
ANNALS OF PLASTIC SURGERY, 2014, 73 (05) :485-491
[17]   Microsurgical Breast Reconstruction for Nipple-Sparing Mastectomy [J].
Tanna, Neil ;
Broer, P. Niclas ;
Weichman, Katie E. ;
Alperovich, Michael ;
Ahn, Christina Y. ;
Allen, Robert J., Sr. ;
Choi, Mihye ;
Karp, Nolan S. ;
Saadeh, Pierre B. ;
Levine, Jamie P. .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2013, 131 (02) :139E-147E