Chiari 1 malformation and raised intracranial pressure

被引：6

作者：

Piper, Rory J. ^{[1
]}

Magdum, Shailendra A. ^{[1
]}

机构：

[1] Oxford Univ Hosp NHS Fdn Trust, John Radcliffe Hosp, Dept Paediat Neurosurg, Level 3,West Wing,Headley Way, Oxford OX3 9DU, England

来源：

CHILDS NERVOUS SYSTEM | 2019年 / 35卷 / 10期

关键词：

Chiari; 1; malformation; Hydrocephalus; Intracranial pressure; I MALFORMATION; CHILDREN; DECOMPRESSION; COMPLICATIONS; MANAGEMENT; SECONDARY; SURGERY;

D O I：

10.1007/s00381-019-04232-x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background The pathophysiology of Chiari 1 malformation (CM1) is inextricably related to intracranial pressure (ICP). The characteristic cerebellar tonsil herniation at the foramen magnum may either cause raised ICP by disturbing CSF flow (as observed in idiopathic CM1) or may itself be the effect of raised ICP (as observed in acquired CM1). Distinguishing between these two phenomena, therefore, is of paramount importance in successfully alleviating the symptoms of the condition and preventing serious complications. Objectives In this article, we discuss the pathophysiology of raised ICP in CM1 and review the current evidence for its investigation and treatment. We also share our own clinical experience which investigates the utility of ICP monitoring in a series of 26 children with CM1.

引用

页码：1719 / 1725

页数：7

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