Premature ovarian insufficiency (POI)

被引：3

作者：

Rehnitz, Julia ^{[1
]}

Strowitzki, Thomas ^{[1
]}

机构：

[1] Univ Frauenklin Heidelberg, Abt Gynakol Endokrinol & Fertilitatsstorungen, Neuenheimer Feld 440, D-69121 Heidelberg, Germany

来源：

GYNAKOLOGE | 2021年 / 54卷 / 07期

关键词：

Amenorrhea; Hypergonadotrophic ovarian insufficiency; Fertility; Genetic mutations; Follicle stimulating hormone; SEX STEROID REPLACEMENT; FRAGILE-X; WOMEN; PREMUTATION; FAILURE;

D O I：

10.1007/s00129-021-04802-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ovarian reserve and follicular maturation are crucial for female fertility. Menopause as the end of the reproductive window generally occurs between the ages of 50 and 52. Approximately 1% of women suffer from a permanent or partly reversible cessation of ovarian function, which is termed premature ovarian insufficiency (POI) or premature ovarian failure (POF) syndrome, before the age of 40 years. The reasons are multifactorial and can be genetic, iatrogenic, autoimmune and infectious. For competent and realistic care and counseling, precise knowledge of causes, diagnostic steps and risks are necessary.

引用

页码：495 / 505

页数：11

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