Towards chiral diamines as chiral catalytic precursors for the borane-mediated enantioselective reduction of prochiral ketones

被引：4

作者：

Basavaiah, Deevi ^{[1
]}

Das, Utpal ^{[1
]}

Roy, Suparna ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

JOURNAL OF CHEMICAL SCIENCES | 2009年 / 121卷 / 06期

关键词：

(3S)-3-Anilinomethyl-1,2,3,4-tetrahydroisoquinoline; (2R)-2-anilinomethylpiperidine; (S)-phenylalanine; asymmetric reduction; P=O STRUCTURAL FRAMEWORK; ASYMMETRIC REDUCTION; ANALOGS;

D O I：

10.1007/s12039-009-0112-x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two chiral diamines (3S)-3-anilinomethyl-1,2,3,4-tetrahydroisoquinoline (1) and (2R)-2-anilinomethylpiperidine (2) have been employed as chiral catalytic sources in the borane-mediated asymmetric reduction of prochiral ketones thus providing the resulting secondary alcohols in good enantiomeric purities (up to 81% ee).

引用

页码：1003 / 1010

页数：8

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