Fragility fractures of the hip and femur: incidence and patient characteristics

被引:205
作者
Nieves, J. W. [1 ,2 ,3 ]
Bilezikian, J. P. [1 ,2 ]
Lane, J. M. [4 ]
Einhorn, T. A. [5 ]
Wang, Y. [6 ]
Steinbuch, M. [6 ]
Cosman, F. [1 ,2 ,3 ]
机构
[1] Columbia Univ, Dept Epidemiol, New York, NY 10027 USA
[2] Columbia Univ, Dept Med, New York, NY USA
[3] Helen Hayes Hosp, Clin Res Ctr, W Haverstraw, NY 10994 USA
[4] Hosp Special Surg, Dept Orthopaed Surg, New York, NY 10021 USA
[5] Boston Univ Orthopaed Surg Associates, Boston, MA 02118 USA
[6] Procter & Gamble Pharmaceut, Epidemiol & Hlth Outcomes, Mason, OH 45040 USA
关键词
Bisphosphonates; Femoral fractures; Femoral shaft; Subtrochanteric; FEMORAL-SHAFT FRACTURES; ALENDRONATE THERAPY; TROCHANTERIC FRACTURES; GEOGRAPHIC PATTERNS; EPIDEMIOLOGY; DIAPHYSEAL; NECK; AGE; HETEROGENEITY; COMPLICATION;
D O I
10.1007/s00198-009-0962-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Using national discharge and medical claims data, we studied the epidemiology of femoral fractures from 1996 to 2006. The annual hip fracture incidence declined from 600/100,000 to 400/100,000, without decline in the more rare femur fractures. Incidence rates for subtrochanteric and femoral shaft fractures were each below 20 per 100,000. This study's purpose is to describe the site-specific epidemiology of femur fractures among people aged 50 and older. Using the National Hospital Discharge Survey from 1996 to 2006 and a large medical claims database (MarketScanA (R)), we studied epidemiology of all femur fractures. Hip fractures were grouped together; subtrochanteric, shaft, and distal femur fractures were kept separate. In females, the overall hospital discharge rates of hip fracture decreased from about 600/100,00 to 400/100,000 person-years from 1996 to 2006. Subtrochanteric, femoral shaft, and lower femur rates remained stable, each approximately 20 per 100,000 person-years. Similar trends but lower rates existed in males. No significant trends were found in any of these fractures during the more recent years of 2002-2006 (MarketScan data). Using MarketScan, the overall incidence of hip fracture was < 300/100,000 person-years; incidence of subtrochanteric and femoral shaft fractures combined was < 25/100,000 person-years and distal femur fracture incidence was < 18/100,000 person-years in females; rates were lower in males. The incidence of hip and other femur fractures increased exponentially with age. We found no evidence of an increasing incidence of any femoral fracture. Hip fracture incidence is declining but the incidence of each of the more rare femur fractures (distal to the lesser trochanter) is stable over time.
引用
收藏
页码:399 / 408
页数:10
相关论文
共 28 条
[1]  
Abrahamsen B, 2009, J BONE MINER RES, V24, P1095, DOI [10.1359/JBMR.081247, 10.1359/jbmr.081247]
[2]  
ARNESON TJ, 1988, CLIN ORTHOP RELAT R, P188
[3]   INCIDENCE OF FEMORAL AND TIBIAL SHAFT FRACTURES - EPIDEMIOLOGY 1950-1983 IN MALMO, SWEDEN [J].
BENGNER, U ;
EKBOM, T ;
JOHNELL, O ;
NILSSON, BE .
ACTA ORTHOPAEDICA SCANDINAVICA, 1990, 61 (03) :251-254
[4]   BILATERAL FRACTURES OF THE FEMORAL-NECK [J].
BOSTON, DA .
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 1982, 14 (03) :207-210
[5]   CONFIDENCE-INTERVALS FOR WEIGHTED SUMS OF POISSON PARAMETERS [J].
DOBSON, AJ ;
KUULASMAA, K ;
EBERLE, E ;
SCHERER, J .
STATISTICS IN MEDICINE, 1991, 10 (03) :457-462
[6]   Possible predisposing factors for the second hip fracture [J].
Dretakis, KE ;
Dretakis, EK ;
Papakitsou, EF ;
Psarakis, S ;
Steriopoulos, K .
CALCIFIED TISSUE INTERNATIONAL, 1998, 62 (04) :366-369
[7]   RELATIVE RATES OF FRACTURE OF THE HIP IN THE UNITED-STATES - GEOGRAPHIC, SEX, AND AGE VARIATIONS [J].
EBERT, FR ;
JACOBSEN, SJ ;
SMITH, GS .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1995, 77A (05) :695-702
[8]   MORPHOLOGY OF THE FEMUR IN PROXIMAL FEMORAL FRACTURES [J].
FERRIS, BD ;
KENNEDY, C ;
BHAMRA, M ;
MUIRHEADALLWOOD, W .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1989, 71 (03) :475-477
[9]   The site-specific epidemiology of hip fracture in the Australian Capital Territory with projections for the first half of the 21st century: Implications for clinical management and health services planning [J].
Fisher, A. A. ;
Davis, M. W. ;
Rubenach, S. E. ;
Le Couteur, D. G. ;
McLean, A. J. .
AUSTRALASIAN JOURNAL ON AGEING, 2007, 26 (01) :45-51
[10]   Trends in hospital care for hip fractures [J].
Gehlbach, S. H. ;
Avrunin, J. S. ;
Puleo, E. .
OSTEOPOROSIS INTERNATIONAL, 2007, 18 (05) :585-591