Optical and biological sensing capabilities of Au2S/AuAgrS coated gold nanorods

被引：41

作者：

Huang, Haowen ^{[1
,3
]}

Liu, Xuanyong ^{[2
,3
]}

Zeng, Yunlong ^{[1
]}

Yu, Xianyong ^{[1
]}

Liao, Bo ^{[1
]}

Yi, Pinggui ^{[1
]}

Chu, Paul K. ^{[3
]}

机构：

[1] Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Ceram, Shanghai 200050, Peoples R China

[3] City Univ Hong Kong, Dept Phys & Mat Sci, Kowloon, Hong Kong, Peoples R China

来源：

BIOMATERIALS | 2009年 / 30卷 / 29期

基金：

中国国家自然科学基金;

关键词：

Biological sensing; Nanorods; Functionalization; Au2S/AuAgS coated gold nanorods; Core-shell nanostructure; Optical properties; QUANTUM DOTS; NANOPARTICLES; GROWTH; SULFIDES; SHAPE; AU2S; CELL;

D O I：

10.1016/j.biomaterials.2009.06.060

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Gold nanorods coated with a multiplex component, namely Au2S/AuAgS coated gold nanorods, are produced without precipitation and aggregation among the nanorods. Both the thickness of the shell and size of the core can be readily controlled by this technique allowing one to tune the plasmon resonance of the nanocomposites over a range of several hundred nanometers. These Au2S/AuAgS coated gold nanorods exhibit interesting optical properties and are suitable for many biological sensing applications. Functionalization of the Au2S/AuAgS coated gold nanorods is achieved by manipulating the affinity between the Au2S/AuAgS and thiol compounds. Biomolecules can be covalently attached via the NH2 bond of the antibodies to the NHS-terminated nanorods. The longitudinal peaks of the Au2S/AuAgS coated gold nanorods are extremely sensitive to the refractive index changes induced by target binding, suggesting that they are excellent sensors for target-specific binding events and have the potential to achieve single-molecule sensitivity in microspectroscopy. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：5622 / 5630

页数：9

共 34 条

[1] Plasmon resonance shifts of Au-coated Au2S nanoshells: Insight into multicomponent nanoparticle growth [J].

Averitt, RD ;

Sarkar, D ;

Halas, NJ .

PHYSICAL REVIEW LETTERS, 1997, 78 (22) :4217-4220

[2] Quantum dots as photosensitizers? [J].

Bakalova, R ;

Ohba, H ;

Zhelev, Z ;

Ishikawa, M ;

Baba, Y .

NATURE BIOTECHNOLOGY, 2004, 22 (11) :1360-1361

[3] 3-D molecular assembly of function in titania-based composite material systems [J].

Bartl, MH ;

Boettcher, SW ;

Frindell, KL ;

Stucky, GD .

ACCOUNTS OF CHEMICAL RESEARCH, 2005, 38 (04) :263-271

[4] Optical properties of gold nanorods: DDA simulations supported by experiments [J].

Brioude, A ;

Jiang, XC ;

Pileni, MP .

JOURNAL OF PHYSICAL CHEMISTRY B, 2005, 109 (27) :13138-13142

[5] Synthesis of TiO2-Au composites by titania-nanorod-assisted generation of gold nanopartictes at aqueous/nonpolar interfaces [J].

Cozzoli, PD ;

Curri, ML ;

Giannini, C ;

Agostiano, A .

SMALL, 2006, 2 (03) :413-421

[6] Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology [J].

Daniel, MC ;

Astruc, D .

CHEMICAL REVIEWS, 2004, 104 (01) :293-346

[7] Si/a-Si core/shell nanowires as nonvolatile crossbar switches [J].

Dong, Yajie ;

Yu, Guihua ;

McAlpine, Michael C. ;

Lu, Wei ;

Lieber, Charles M. .

NANO LETTERS, 2008, 8 (02) :386-391

[8] Small is different: Shape-, size-, and composition-dependent properties of some colloidal semiconductor nanocrystals [J].

El-Sayed, MA .

ACCOUNTS OF CHEMICAL RESEARCH, 2004, 37 (05) :326-333

[9] Dependence of the gold nanorod aspect ratio on the nature of the directing surfactant in aqueous solution [J].

Gao, JX ;

Bender, CM ;

Murphy, CJ .

LANGMUIR, 2003, 19 (21) :9065-9070

[10] Fine-tuning the shape of gold nanorods [J].

Gou, LF ;

Murphy, CJ .

CHEMISTRY OF MATERIALS, 2005, 17 (14) :3668-3672

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