Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

被引：67

作者：

Ahn, KS

Sim, WS

Lee, IK

Seu, YB

Kim, IH

机构：

[1] KOREA UNIV,GRAD SCH BIOTECHNOL,SEOUL 136701,SOUTH KOREA

[2] KOREA UNIV,DEPT BIOL,SEOUL 136701,SOUTH KOREA

[3] KIST,KOREA RES INST BIOSCI & BIOTECHNOL,TAEJON 305600,SOUTH KOREA

[4] KYUNGPOOK NATL UNIV,DEPT MICROBIOL,TAEGU 702701,SOUTH KOREA

来源：

PLANTA MEDICA | 1997年 / 63卷 / 04期

关键词：

D O I：

10.1055/s-2006-957701

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC As a result of the structure analysis by mass, IR, H-1-MMR, and C-13-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

引用

页码：360 / 361

页数：2

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