Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

被引：67
作者：
Ahn, KS
Sim, WS
Lee, IK
Seu, YB
Kim, IH
机构：
[1] KOREA UNIV,GRAD SCH BIOTECHNOL,SEOUL 136701,SOUTH KOREA
[2] KOREA UNIV,DEPT BIOL,SEOUL 136701,SOUTH KOREA
[3] KIST,KOREA RES INST BIOSCI & BIOTECHNOL,TAEJON 305600,SOUTH KOREA
[4] KYUNGPOOK NATL UNIV,DEPT MICROBIOL,TAEGU 702701,SOUTH KOREA
来源：
PLANTA MEDICA | 1997年 / 63卷 / 04期
关键词：
D O I：
10.1055/s-2006-957701
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC As a result of the structure analysis by mass, IR, H-1-MMR, and C-13-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.
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页码：360 / 361
页数：2
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