RETRACTED: ANTIBACTERIAL COMPOSITE LAYERS ON Ti: ROLE OF ZNO NANOPARTICLES (Retracted Article)

被引:3
作者
Roguska, A. [1 ]
Belcarz, A. [2 ]
Suchecki, P. [3 ]
Andrzejczuk, M. [3 ]
Lewandowska, M. [3 ]
机构
[1] Polish Acad Sci, Inst Phys Chem, Warsaw, Poland
[2] Med Univ Lublin, Chair & Dept Biochem & Biotechnol, Lublin, Poland
[3] Warsaw Univ Technol, Fac Mat Sci & Engn, Warsaw, Poland
关键词
bone implants; TiO2; nanotubes; ZnO nanoparticles; Staphylococcus epidermidis; antibacterial properties; BACTERIA;
D O I
10.1515/amm-2016-0039
中图分类号
TF [冶金工业];
学科分类号
0806 ;
摘要
Problem of Post-operative infections of implant materials caused by bacterial adhesion to their surfaces is very serious. Enhancement of antibacterial properties is potentially beneficial for biomaterials value. Therefore, the metallic and metallic oxide nanoparticles attract particular attention as antimicrobial factors. The aim of this work was to create nanotubular (NT) oxide layers on Ti with the addition of ZnO nanoparticles, designed for antibacterial biomedical coatings. Antimicrobial activities of titanium, TiO2 NT and ZnO/TiO2 NT surfaces were evaluated against bacterial strain typical for orthopaedic infections: S. epidermidis. TiO2 NT alone killed the free bacterial cells significantly but promoted their adhesion to the surfaces. The presence of moderate amount of ZnO nanoparticles significantly reduced the S. epidermidis cells adhesion and viability of bacterial cells in contact with modified surfaces. However, higher amount of loaded nanoZnO showed the reduced antimicrobial properties than the medium amount, suggesting the overdose effect.
引用
收藏
页码:213 / 216
页数:4
相关论文
共 15 条
[1]   Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium [J].
Brayner, R ;
Ferrari-Iliou, R ;
Brivois, N ;
Djediat, S ;
Benedetti, MF ;
Fiévet, F .
NANO LETTERS, 2006, 6 (04) :866-870
[2]   Surface functionalization of titanium with hyaluronic acid/chitosan polyelectrolyte multilayers and RGD for promoting osteoblast functions and inhibiting bacterial adhesion [J].
Chua, Poh-Hui ;
Neoh, Koon-Gee ;
Kang, En-Tang ;
Wang, Wilson .
BIOMATERIALS, 2008, 29 (10) :1412-1421
[3]  
GRISTINA AG, 1994, CLIN ORTHOP RELAT R, P106
[4]   Evaluation and treatment of infection at the site of a total hip of knee arthroplasty [J].
Hanssen, AD ;
Rand, JA .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1998, 80A (06) :910-922
[5]   "Nanoantibiotics": A new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era [J].
Huh, Ae Jung ;
Kwon, Young Jik .
JOURNAL OF CONTROLLED RELEASE, 2011, 156 (02) :128-145
[6]  
Japanese Industrial Standards, 2000, Z28012000 JIS, V2801
[7]   Osteogenic activity and antibacterial effect of zinc ion implanted titanium [J].
Jin, Guodong ;
Cao, Huiliang ;
Qiao, Yuqin ;
Meng, Fanhao ;
Zhu, Hongqin ;
Liu, Xuanyong .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 117 :158-165
[8]  
Nair S., 2009, J MAT SCI MAT M, VM.20, P253
[9]   Decreased Staphylococcus epidermis adhesion and increased osteoblast functionality on antibiotic-loaded titania nanotubes [J].
Popat, Ketul C. ;
Eltgroth, Matthew ;
LaTempa, Thomas J. ;
Grimes, Craig A. ;
Desai, Tejal A. .
BIOMATERIALS, 2007, 28 (32) :4880-4888
[10]   Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation [J].
Premanathan, Mariappan ;
Karthikeyan, Krishnamoorthy ;
Jeyasubramanian, Kadarkaraithangam ;
Manivannan, Govindasamy .
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2011, 7 (02) :184-192