Enantioselective separations of chiral molecules by mu-HPLC and SFC on microbore and packed microcapillary columns

被引：0

作者：

DAcquarica, I

Gasparrini, F

Giannoli, B

Misiti, D

Villani, C

Mapelli, GP

机构：

[1] UNIV ROMA LA SAPIENZA,DIPARIMENTO STUDI CHIM & TECNOL SOSTANZE BIOL ATT,I-00185 ROME,ITALY

[2] CE INSTRUMENTS,I-20090 RODANO,MILANO,ITALY

来源：

HRC-JOURNAL OF HIGH RESOLUTION CHROMATOGRAPHY | 1997年 / 20卷 / 05期

关键词：

SFC; mu-HPLC; chiral microbore and microcapillary columns; enantioselective chromatography; multicolumns enantioselective chromatography;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

New results obtained with microbore or microcapillary columns packed with DACH-DNB CSP (spherical silica, 5 mu m) using conventional LC eluents or supercritical fluids are reported, Examples of direct chromatographic separations of complex mixtures of stereoisomers on: a) long, packed microbore or microcapillary columns and b) several columns coupled in series are shown; in the latter case, a home-made calculation procedure (Simulation for Multi-Column Chromatography - SMCC) was used to quickly select the optimal conditions (kind of stationary phases and relative columns length).

引用

页码：261 / 264

页数：4

共 10 条

[1]

Allenmark S. G., 1991, CHROMATOGRAPHIC ENAN

[2] ENANTIOMERIC SEPARATION OF AMINO-ALCOHOLS ON DINITROBENZOYL-DIAMINOCYCLOHEXANE CHIRAL STATIONARY PHASES [J].