The Norwood procedure using a right ventricle-pulmonary artery conduit: Comparison of the right-sided versus left-sided conduit position

被引:37
作者
Barron, David J. [1 ]
Brooks, Andre [1 ]
Stickley, John [1 ]
Woolley, Steven M. [1 ]
Stuemper, Oliver [2 ]
Jones, Timothy J. [1 ]
Brawn, William J. [1 ]
机构
[1] Birmingham Childrens Hosp, Dept Cardiac Surg, Birmingham B4 6NH, W Midlands, England
[2] Birmingham Childrens Hosp, Dept Pediat Cardiol, Birmingham B4 6NH, W Midlands, England
关键词
LEFT-HEART SYNDROME; 1ST-STAGE PALLIATION; SHUNT; HEMODYNAMICS; MORTALITY; GROWTH;
D O I
10.1016/j.jtcvs.2009.05.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: We proposed that a right-sided right ventricle-pulmonary artery conduit during the stage I Norwood procedure would facilitate pulmonary artery reconstruction during the stage II procedure. Methods: Between 2002 and 2006, 153 patients underwent Norwood stage I reconstruction with a right ventricle-pulmonary artery conduit (125 in the right-sided group and 28 in the left-sided group). The previous 150 consecutive classic Norwood procedures (1997-2002) were used as a control group. Outcomes from stages I and II were analyzed, including ventricular function and pulmonary artery morphology. Results: The 30-day survival was 88%(110/125) in the right-sided group, 75%(21/28) in the left-sided group, and 70%(105/150) in the control group (P <.001, right-sided vs control groups). The conduit length was 35 +/- 9 mm in the right-sided group and 26 +/- 8 mm in the left-sided group (P = .001). Survival at 6 months demonstrated a significant survival benefit in the right-sided right ventricle-pulmonary artery conduit group over the control group (P = .009, log-rank test). There was no difference in ventricular function between the groups and no regional dyskinesia associated with the right ventricle-pulmonary artery conduit. Despite larger branch pulmonary artery size in the right ventricle-pulmonary artery conduit groups (compared with the control group), central pulmonary artery stenoses were common (62% in the right conduit and 80% in the left conduit). Bypass and ischemic times at stage II were 49 +/- 10 and 23 +/- 13 minutes in the right-sided group compared with 61.5 +/- 9.5 and 31 +/- 14 minutes in the left-sided group (P <.001 and P = .03, respectively). The 30-day mortality after the stage II procedure was 1.3%(1/76) in the right-sided group, 0%(0/18) in the left-sided group, and 3.3%(3/90) in the control group. Conclusion: The right-sided conduit is a safe technique and has improved 30-day and overall post-stage II survival compared with that seen with the classic Norwood procedure. The right ventricle-pulmonary artery conduit is associated with central pulmonary artery stenosis but good development of the branch pulmonary arteries and preservation of ventricular function. The right-sided conduit significantly reduces cardiopulmonary bypass times at stage II.
引用
收藏
页码:528 / 537
页数:10
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