Surgical Outcome in Patients with Oral Verrucous Carcinoma: Long-Term Follow-Up in an Endemic Betel Quid Chewing Area

被引:10
作者
Huang, Tung-Tsun [3 ,4 ]
Hsu, Lee-Ping [1 ,3 ]
Hsu, Yung-Hsiang [2 ,3 ]
Chen, Peir-Rong [1 ,3 ]
机构
[1] Buddhist Tzu Chi Gen Hosp, Dept Otolaryngol, Hualien 970, Taiwan
[2] Buddhist Tzu Chi Gen Hosp, Dept Pathol, Hualien 970, Taiwan
[3] Tzu Chi Univ, Sch Med, Hualien, Taiwan
[4] Buddhist Tzu Chi Gen Hosp, Taipei Branch, Dept Otolaryngol, Taipei, Taiwan
来源
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES | 2009年 / 71卷 / 06期
关键词
Oral cavity cancer; Verrucous carcinoma; Second primary tumor; Multiple primary tumor; Betel quid; SQUAMOUS-CELL CARCINOMA; MULTIPLE-PRIMARY-TUMORS; CAVITY; CANCER; NECK; HEAD; RADIOTHERAPY; TAIWAN; EPIDEMIOLOGY; EMPHASIS;
D O I
10.1159/000267306
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background/Aims: To evaluate the clinical features and prognosis of patients with oral verrucous carcinoma (OVC) in an endemic betel quid chewing area. Methods: A retrospective review was conducted in 39 patients with OVC treated surgically from 1991 to 2002. Results: Thirty-seven patients (94.9%) were male. The median age at diagnosis was 53.8 years. All patients had been exposed to betel quid, cigarette smoking, and/or alcohol. The most common site of tumor origin was the buccal mucosa (64.1%). The tumor control rate was 97.4% after the first surgical procedure. Second/multiple primary tumors (SPTs/MPTs) were found in 21 patients. There were 13 deaths during the follow-up period, with SPTs/MPTs being the most common cause. The cancer-specific survival rate was 89.1% at 5 years, but continued to decrease thereafter. Conclusion: Surgery was effective for controlling OVC. However, long-term follow-up was necessary because of the high incidence of SPTs/MPTs and its impact on patient survival. Copyright (C) 2009 S. Karger AG, Basel
引用
收藏
页码:323 / 328
页数:6
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