Surgical Outcome in Patients with Oral Verrucous Carcinoma: Long-Term Follow-Up in an Endemic Betel Quid Chewing Area

被引：10

作者：

Huang, Tung-Tsun ^{[3
,4
]}

Hsu, Lee-Ping ^{[1
,3
]}

Hsu, Yung-Hsiang ^{[2
,3
]}

Chen, Peir-Rong ^{[1
,3
]}

机构：

[1] Buddhist Tzu Chi Gen Hosp, Dept Otolaryngol, Hualien 970, Taiwan

[2] Buddhist Tzu Chi Gen Hosp, Dept Pathol, Hualien 970, Taiwan

[3] Tzu Chi Univ, Sch Med, Hualien, Taiwan

[4] Buddhist Tzu Chi Gen Hosp, Taipei Branch, Dept Otolaryngol, Taipei, Taiwan

来源：

ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES | 2009年 / 71卷 / 06期

关键词：

Oral cavity cancer; Verrucous carcinoma; Second primary tumor; Multiple primary tumor; Betel quid; SQUAMOUS-CELL CARCINOMA; MULTIPLE-PRIMARY-TUMORS; CAVITY; CANCER; NECK; HEAD; RADIOTHERAPY; TAIWAN; EPIDEMIOLOGY; EMPHASIS;

D O I：

10.1159/000267306

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background/Aims: To evaluate the clinical features and prognosis of patients with oral verrucous carcinoma (OVC) in an endemic betel quid chewing area. Methods: A retrospective review was conducted in 39 patients with OVC treated surgically from 1991 to 2002. Results: Thirty-seven patients (94.9%) were male. The median age at diagnosis was 53.8 years. All patients had been exposed to betel quid, cigarette smoking, and/or alcohol. The most common site of tumor origin was the buccal mucosa (64.1%). The tumor control rate was 97.4% after the first surgical procedure. Second/multiple primary tumors (SPTs/MPTs) were found in 21 patients. There were 13 deaths during the follow-up period, with SPTs/MPTs being the most common cause. The cancer-specific survival rate was 89.1% at 5 years, but continued to decrease thereafter. Conclusion: Surgery was effective for controlling OVC. However, long-term follow-up was necessary because of the high incidence of SPTs/MPTs and its impact on patient survival. Copyright (C) 2009 S. Karger AG, Basel

引用

页码：323 / 328

页数：6

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