Triterpenoid Saponins from Rubus ellipticus var. obcordatus

被引：71

作者：

Li, Wei ^{[1
]}

Fu, Hongwei ^{[1
,2
]}

Bai, Hong ^{[3
]}

Sasaki, Tatsunori ^{[1
]}

Kato, Hiroyoshi ^{[1
]}

Koike, Kazuo ^{[1
]}

机构：

[1] Toho Univ, Fac Pharmaceut Sci, Chiba 2748510, Japan

[2] Zhejiang Univ, Dept Biomed Engn, Zhejiang Prov Key Lab Chinese Med Screening Explo, Key Lab Biomed Engn Minist Educ, Hangzhou 310027, Peoples R China

[3] Shandong Acad Med Sci, Inst Mat Med, Jinan 250062, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 10期

关键词：

PENTACYCLIC TRITERPENOIDS; STEM BARK; GLUCOSIDES; LEAVES; PLANTS;

D O I：

10.1021/np900237a

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Ten new triterpenoid saponins (1-10), named rubusides A-J, and 21 known saponins (11-31) were isolated from the roots of Rubus ellipticus var. obcordatus. The structures of 1-10 were established on the basis of spectroscopic analyses, mainly NMR and MS, and chemical degradations. The compounds demonstrated inhibitory activities against (X-glucosidase with IC(50) values in the range 0.65-3.09 mM.

引用

页码：1755 / 1760

页数：6

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