Resistance to macrolides in Group A streptococci from the European section of Turkey:: genetic and phenotypic characterization

被引：8
作者：
Akata, F [1 ]
Öztürk, D
Tansel, Ö
Tatman-Otkun, M
Otkun, M
Fitoussi, F
Bingen, E
Tugrul, M
机构：
[1] Trakya Univ, Fac Med, Dept Clin Bacteriol & Infect Dis, TR-22060 Edirne, Turkey
[2] Hop Robert Debre, Microbiol Serv, F-75019 Paris, France
来源：
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2002年 / 20卷 / 06期
关键词：
Group A streptococci; macrolide resistance; resistance phenotype; mefA; ermTR;
D O I：
10.1016/S0924-8579(02)00241-8
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The aim of this study was to determine the susceptibilities to macrolides of Group A streptococcal isolates from the European section of Turkey. In the case of resistant isolates, the patterns and genetic mechanisms of erythromycin resistance were studied. Seven (2.7%) of the 260 isolates were resistant to erythromycin. Four of them showed the M phenotype and harboured mefA genes whereas three isolates showed the inducible macrolide, lincosamide and streptogramin B resistance phenotype and harboured ermTR genes. In the European section of Turkey, the current resistance rate of Group A streptococci to macrolides remains low. (C) 2002 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码：461 / 463
页数：3
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