Simplified intraoperative parathormone assay for primary hyperparathyroidism in a resource-limited setting

被引:0
|
作者
Rajan, Sendhil [1 ]
Ravindhran, Bharadhwaj [1 ]
George, Belinda [2 ]
Bantwal, Ganapathy [2 ]
Ayyar, Vaagesh [2 ]
Manjuanth, Suraj [3 ]
机构
[1] St Johns Med Coll, Dept Gen Surg, Bengaluru, India
[2] St Johns Med Coll, Dept Endocrinol, Bengaluru, India
[3] St Johns Med Coll, Dept Surg Oncol, Bengaluru, India
关键词
intraoperative care; parathormone decline; parathyroidectomy; prediction;
D O I
10.2217/bmm-2020-0225
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: The optimum threshold of IOPTH decay remains a debate and numerous criteria have been described. In this study, we utilize a single-sample IOPTH taken 10 min post excision. Materials & methods: This 4-year query of a prospectively maintained database included primary hyperparathyroidism patients with pre-operative PTH done 1 week prior to surgery, and a 10-min post excision IOPTH value. Optimal cut-off for PTH and sensitivity/specificity were calculated. Results: A total of 93 patients had single-gland disease, of whom 79 (84.9%) were symptomatic. The 10-min post excision assay sensitivity in single-gland disease was 97.8% (50% fall), 95% (60% fall) and 83.9% (70% fall). Conclusion: A post excision single-shot IOPTH assay with a 50% fall offers a sensitivity of 97.8% in patients of primary hyperparathyroidism with single-gland benign disease.
引用
收藏
页码:331 / 336
页数:6
相关论文
共 50 条
  • [1] Management of primary spontaneous pneumothorax in a resource-limited setting
    Al-Ani M.S.
    AL-Khattaby L.M.
    Kakamad F.H.
    Indian Journal of Thoracic and Cardiovascular Surgery, 2015, 31 (4) : 290 - 293
  • [2] IS SERUM PARATHORMONE ASSAY NECESSARY IN EVALUATING PRIMARY HYPERPARATHYROIDISM
    POOLE, GV
    ALBERTSON, DA
    MYERS, RT
    AMERICAN SURGEON, 1986, 52 (03) : 170 - 173
  • [3] FOOD ALLERGY IN THE RESOURCE-LIMITED SETTING
    Gray, Claudia L.
    CURRENT ALLERGY & CLINICAL IMMUNOLOGY, 2023, 36 (01) : 20 - 26
  • [4] Clinical metagenomics in a resource-limited setting
    Marais, Gert
    Valley-Omar, Ziyaad
    Marais, Suzaan
    Mcmullen, Kate
    Bateman, Kathleen
    Westhuizen, Diederick van der
    Maseko, Moepeng
    Hardie, Diana
    Brink, Adrian
    JOURNAL OF INFECTION, 2023, 87 (06) : 604 - 606
  • [5] Asymptomatic vs Symptomatic Primary Hyperparathyroidism: Comparison of Clinico-investigative Profile and Surgical Outcomes in Resource-Limited Setting
    Puthenveetil, Pradeep
    Panchangam, Ramkanth Bhargav
    INDIAN JOURNAL OF SURGERY, 2022, 84 (01) : 100 - 103
  • [6] The Evaluation of Lymphadenopathy in a Resource-Limited Setting
    Ali, Mohammed
    Elhatw, Ahmed
    Hegazy, Mai
    Albeyoumi, Hossam
    Sakr, Noha
    Deyab, Ashrakat M.
    Soliman, Ammar Yasser
    Said, Ebram
    Elbehwashy, Ahmad Samir
    Nassar, Mahmoud
    Alfishawy, Mostafa
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (10)
  • [7] Asymptomatic vs Symptomatic Primary Hyperparathyroidism: Comparison of Clinico-investigative Profile and Surgical Outcomes in Resource-Limited Setting
    Pradeep Puthenveetil
    Ramkanth Bhargav Panchangam
    Indian Journal of Surgery, 2022, 84 : 100 - 103
  • [8] Primary bladder neck obstruction (PBNO) in children in a resource-limited setting
    Mugalo, E. Lumadede
    Akello, W. Abila
    Mburu, Nditika E.
    Kimani, Wnfred
    Rono, D. Kipkemoi
    Musau, Pius
    UROLOGY CASE REPORTS, 2022, 44
  • [9] Intraoperative chemiluminometric assay for simplified localization of parathyroid adenomas during surgery for primary hyperparathyroidism
    Bergert, H
    Zimmermann, T
    Ockert, D
    Alldinger, I
    Kersting, S
    Saeger, HD
    TALANTA, 2003, 60 (2-3) : 617 - 621
  • [10] Intraoperative parathormone measurement in patients with primary hyperparathyroidism - A prospective clinical study
    Beck, TM
    Huber, PR
    Oertli, D
    SWISS MEDICAL WEEKLY, 2003, 133 (13-14) : 206 - 209