Saponin with antibacterial activity from the roots of Albizia adianthifolia

被引：19

作者：

Sonfack, Gaielle ^{[1
]}

Tchinda, Cedric Fossi ^{[2
,3
]}

Simo, Ingrid Konga ^{[1
]}

Bitchagno, Gabin Thierry M. ^{[1
,4
]}

Nganou, Blaise Kemajou ^{[1
]}

Celik, Ilhami ^{[5
]}

Tene, Mathieu ^{[1
]}

Gorkem, Sultan Funda ^{[5
]}

Opatz, Till ^{[4
]}

Beng, Veronique Penlap ^{[3
]}

Kuete, Victor ^{[2
]}

Tane, Pierre ^{[1
]}

机构：

[1] Univ Dschang, Fac Sci, Dept Chem, Dschang, Cameroon

[2] Univ Dschang, Fac Sci, Dept Biochem, Dschang, Cameroon

[3] Univ Yaounde I, Fac Sci, Dept Biochem, Yaounde, Cameroon

[4] Johannes Gutenberg Univ Mainz, Inst Organ Chem, Mainz, Germany

[5] Eskisehir Tech Univ, Fac Sci, Dept Chem, Eskisehir, Turkey

来源：

NATURAL PRODUCT RESEARCH | 2021年 / 35卷 / 17期

关键词：

Albizia adianthifolia; Mimosaceae; saponin; adianthifolioside; antibacterial; TRITERPENOID SAPONINS; ANTIMICROBIAL ACTIVITY; STEM BARK; FRACTIONS; EXTRACT; ACID;

D O I：

10.1080/14786419.2019.1672689

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repeated open column chromatography methods and spectroscopic followed by spectrometric techniques. The isolated compounds were tested against eleven Gram-negative bacteria including multidrug resistant strains. The results revealed considerable inhibition of the new saponin against the studied bacteria with MIC values ranging from 16 to 128??g/mL.

引用

页码：2831 / 2839

页数：9

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