Efficient preparation of vinylcyclopropane by S-N' cyclization of the organolithium derived from (E)-5-iodo-1-methoxy-2-pentene

被引：18

作者：

Bailey, WF

Tao, Y

机构：

[1] Department of Chemistry, University of Connecticut, Storrs

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 35期

关键词：

D O I：

10.1016/S0040-4039(97)01423-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(5-Methoxy-E-3-pentenyl)lithium (1), which may be prepared in virtually quantitative yield from the corresponding iodide by low-temperature lithium-iodine exchange, cyclizes with expulsion of the allylic methoxy on warming in the presence of TMEDA to afford vinylcyclopropane in 88 % yield. (C) 1997 Elsevier Science Ltd.

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页码：6157 / 6158

页数：2

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