Psychosocial, attitudinal, and demographic correlates of cancer-related germline genetic testing in the 2017 Health Information National Trends Survey

被引：7

作者：

Roberts, Megan C. ^{[1
]}

Turbitt, Erin ^{[2
]}

Klein, William M. P. ^{[1
,2
]}

机构：

[1] NCI, 9609 Med Ctr Dr, Rockville, MD 20850 USA

[2] NHGRI, 31 Ctr Dr, Bethesda, MD 20892 USA

来源：

JOURNAL OF COMMUNITY GENETICS | 2019年 / 10卷 / 04期

关键词：

Genetic testing; BRCA1; 2; Lynch syndrome; Uptake; Cancer; Psychosocial factors; Health beliefs; RISK-ASSESSMENT; GENOMIC MEDICINE; BREAST; WOMEN; INSIGHTS; DECISIONS; KNOWLEDGE; AWARENESS; OVARIAN; CARE;

D O I：

10.1007/s12687-018-00405-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The study objective was to examine bivariate and multivariate associations among worry, perceptions, attitudes, sociodemographics, and uptake of cancer-related germline genetic testing. We used data from the Health Information National Trends Survey (cycle 5.1), administered (January-May 2017) to a nationally representative sample of non-institutionalized adults (n = 3285). Those who had "heard about genetic tests that determine how a disease can be treated" had a higher likelihood of Lynch syndrome and BRCA1/2 testing (aRR = 2.57, p < 0.01; aRR = 3.23, p < 0.04). Attitudinal and psychosocial variables were not associated with uptake. Future research should explore ways to educate the public about the potential use of genetics in treatment decision-making.

引用

页码：453 / 459

页数：7

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