Arene-Free Ruthenium(II/IV)-Catalyzed Bifurcated Arylation for Oxidative C-H/C-H Functionalizations

被引：42

作者：

Rogge, Torben ^{[1
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Georg August Univ Gottingen, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 44期

关键词：

C-H activation; density functional calculations; oxidative catalysis; reaction mechanisms; ruthenium; CATALYZED DIRECT ARYLATION; BOND ACTIVATION; MECHANISTIC INSIGHT; AROMATIC-COMPOUNDS; BENZOIC-ACIDS; ARYL; WATER; CHLORIDES; HYDROSILYLATION; SELECTIVITY;

D O I：

10.1002/anie.201909457

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Experimental and computational studies provide detailed insight into the selectivity- and reactivity-controlling factors in bifurcated ruthenium-catalyzed direct C-H arylations and dehydrogenative C-H/C-H functionalizations. Thorough investigations revealed the importance of arene-ligand-free complexes for the formation of biscyclometalated intermediates within a ruthenium(II/IV/II) mechanistic manifold.

引用

收藏

页码：15640 / 15645

页数：6

相关论文

共 50 条

[21] Ruthenium-Catalyzed C-H Arylation and Alkenylation of Furfural Imines with Boronates [J].

Siopa, Filipa ;

Cladera, Valerie-Anne Ramis ;

Mateus Afonso, Carlos Alberto ;

Oble, Julie ;

Poli, Giovanni .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 2018 (44) :6101-6106

[22] Ruthenium-Catalyzed C-H Bond Activation/Arylation Accelerated by Biomass-Derived Ligands [J].

Binnani, Chinky ;

Mandal, Shyama Charan ;

Pathak, Biswarup ;

Singh, Sanjay K. .

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2019, 2019 (23) :2844-2852

[23] Solvent-Free Ruthenium(II)-Catalyzed C-H Activation: Synthesis of Alkenylarylpyrazole Derivatives [J].

Shome, Sanchari ;

Singh, Surya Prakash .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 2015 (27) :6025-6032

[24] Ruthenium-Catalyzed Oxidative Annulation by Cleavage of C-H/N-H Bonds [J].

Ackermann, Lutz ;

Lygin, Alexander V. ;

Hofmann, Nora .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (28) :6379-6382

[25] Palladium(II)-Catalyzed Oxidative C-H/C-H Cross-Coupling of Heteroarenes [J].

Xi, Peihua ;

Yang, Fan ;

Qin, Song ;

Zhao, Dongbing ;

Lan, Jingbo ;

Gao, Ge ;

Hu, Changwei ;

You, Jingsong .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (06) :1822-+

[26] Ruthenium-Catalyzed C-H Arylation of Benzoic Acids and Indole Carboxylic Acids with Aryl Halides [J].

Simonetti, Marco ;

Cannas, Diego M. ;

Panigrahi, Adyasha ;

Kujawa, Szymon ;

Kryjewski, Michal ;

Xie, Pan ;

Larrosa, Igor .

CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (03) :549-553

[27] Deciphering the Role of Silver in Palladium-Catalyzed C-H Functionalizations [J].

Bhattacharya, Trisha ;

Dutta, Subhabrata ;

Maiti, Debabrata .

ACS CATALYSIS, 2021, 11 (15) :9702-9714

[28] C-H Activation of π-Arene Ruthenium Complexes [J].

Wilkinson, Luke A. ;

Pike, Jack A. ;

Walton, James W. .

ORGANOMETALLICS, 2017, 36 (22) :4376-4381

[29] Ruthenium-Catalyzed Dehydrogenative Aromatic C-H Silylation of Benzamides with Hydrosilanes [J].

Takada, Kosuke ;

Hanataka, Tsurugi ;

Namikoshi, Takeshi ;

Watanabe, Shinji ;

Murata, Miki .

ADVANCED SYNTHESIS & CATALYSIS, 2015, 357 (10) :2229-2232

[30] Ruthenium(II)-Catalyzed Decarboxylative C-H Activation: Versatile Routes to meta-Alkenylated Arenes [J].

Kumar, N. Y. Phani ;

Bechtoldt, Alexander ;

Raghuvanshi, Keshav ;

Ackermann, Lutz .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (24) :6929-6932

← 1 2 3 4 5 →