Synthesis, antimicrobial, and anti-inflammatory activities of acetamido pyrrolyl azoles

被引：16

作者：

Sowmya, Donthamsetty V. ^{[1
]}

Basha, Shaik Sharafuddin ^{[1
]}

Devi, Palampalli Uma Maheswari ^{[2
]}

Lavanyalatha, Yerraguravagari ^{[2
]}

Padmaja, Adivireddy ^{[1
]}

Padmavathi, Venkatapuram ^{[1
]}

机构：

[1] Sri Venkateswara Univ, Tirupati, Andhra Prades, India

[2] Sri Padmavathi Mahilavisvavidyalayam, Tirupati, Andhra Prades, India

来源：

MEDICINAL CHEMISTRY RESEARCH | 2017年 / 26卷 / 05期

关键词：

Pyrrole; Oxazole; Thiazole; Imidazole; Antimicrobial activity; Anti-inflammatory activity; LINKED BIS; DERIVATIVES; INHIBITORS; THIAZOLES; SERIES; AGENTS;

D O I：

10.1007/s00044-017-1801-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The acetamido pyrrolyl oxazoles/thiazoles/imidazoles were prepared and tested for their antimicrobial and anti-inflammatory activities. The nitro substituted acetamido pyrrolyl thiazole (11f) and pyrrolyl imidazole (12f) exhibited promising antibacterial activity against K. pneumoniae. The compound 12f showed good antifungal activity against P. chrysogenum. The methoxy acetamido pyrrolyl oxazole (10c) displayed potential anti-inflammatory activity.

引用

页码：1010 / 1021

页数：12

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