Inflammatory myofibroblastic tumor

被引:12
|
作者
Leuschner, I. [1 ]
机构
[1] Univ Klinikum Schleswig Holstein, Inst Pathol, Sekt Kinderpathol, GPOH, D-24105 Kiel, Germany
来源
PATHOLOGE | 2010年 / 31卷 / 02期
关键词
Inflammatory myofibroblastic tumor; Soft tissue tumor; Spindle cell lesion; Immunohistochemistry; FIBROSARCOMA; PSEUDOTUMOR;
D O I
10.1007/s00292-009-1262-9
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Inflammatory myofibroblastic tumor (IMT) is a soft tissue lesion which can be found in almost all parts of the human body, but shows the highest incidence in the abdomen. It is a spindle cell lesion with prominent inflammatory infiltrate which consists predominantly of plasma cells. Using immunohistochemistry a myofibroblastic differentiation can be demonstrated. ALK is expressed in approximately 50% of tumors. The tumors are associated with a benign behavior but recurrences occur in about one third of abdominal cases. Malignant cases are rare.
引用
收藏
页码:106 / 108
页数:3
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