A systematic comparison of rheumatoid arthritis and ankylosing spondylitis: non-steroidal anti-inflammatory drugs

被引：0
作者：
Poddubnyy, D. [1 ]
Song, I-H. [1 ]
Sieper, J. [1 ]
机构：
[1] Charite, Dept Rheumatol, D-12200 Berlin, Germany
来源：
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | 2009年 / 27卷 / 04期
关键词：
Ankylosing spondylitis; rheumatoid arthritis; NSAID; CLINICAL-TRIAL; DOUBLE-BLIND; NAPROXEN; ETORICOXIB; CELECOXIB; RISK; DICLOFENAC; OSTEOARTHRITIS; COMPLICATIONS; METAANALYSIS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Non-steroidal anti-inflammatory drugs (NSAIDs) play different roles in the management of patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS). In RA there is minimal evidence that NSAIDs are able to alter the course of disease or prevent joint destruction and, therefore, they should mostly be used as a short-term bridging therapy In contrast to RA. in AS NSAIDs are considered as a cornerstone of the treatment not only because of a high symptomatic efficacy, but also because they might even retard osteoproliferation and radiographic progression. Considering younger age of AS patients and lower prevalence of comorbidities, they are probably at lower risk for cardiovascular and gastrointestinal side effects of short- and long-term NSAID therapy in comparison to RA.
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页码：S148 / S151
页数：4
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