Acquired BCR-ABL1 fusion and IDH1 clonal evolution following BCL2 inhibitor treatment in refractory acute myeloid leukemia

被引：0

作者：

Adrianzen-Herrera, Diego ^{[1
]}

Jordan-Bruno, Ximena ^{[1
]}

Devitt, Katherine A. ^{[2
]}

Conant, Joanna L. ^{[2
]}

Gardner, Juli-Anne ^{[2
]}

机构：

[1] Univ Vermont, Div Hematol & Oncol, Larner Coll Med, 89 Beaumont Ave,Given Bldg,E-214, Burlington, VT 05405 USA

[2] Univ Vermont, Dept Pathol & Lab Med, Larner Coll Med, Burlington, VT USA

来源：

LEUKEMIA RESEARCH | 2021年 / 100卷

关键词：

PHILADELPHIA-CHROMOSOME; TRANSLOCATION; AML;

D O I：

10.1016/j.leukres.2020.106494

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页数：3

共 20 条

[1] Emergence of BCR-ABL1 Fusion in AML Post-FLT3 Inhibitor-Based Therapy: A Potentially Targetable Mechanism of Resistance - A Case Series [J].

Alotaibi, Ahmad S. ;

Yilmaz, Musa ;

Loghavi, Sanam ;

DiNardo, Courtney ;

Borthakur, Gautam ;

Kadia, Tapan M. ;

Thakral, Beenu ;

Pemmaraju, Naveen ;

Issa, Ghayas C. ;

Konopleva, Marina ;

Short, Nicholas J. ;

Patel, Keyur ;

Tang, Guilin ;

Ravandi, Farhad ;

Daver, Naval .

FRONTIERS IN ONCOLOGY, 2020, 10

[2] Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations [J].

Bacher, Ulrike ;

Haferlach, Torsten ;

Alpermann, Tamara ;

Zenger, Melanie ;

Hochhaus, Andreas ;

Beelen, Dietrich W. ;

Uppenkamp, Michael ;

Rummel, Mathias ;

Kern, Wolfgang ;

Schnittger, Susanne ;

Haferlach, Claudia .

BRITISH JOURNAL OF HAEMATOLOGY, 2011, 152 (06) :713-720

[3] Co-occurrence of chronic myeloid leukemia with chronic lymphocytic leukemia: a report of two cases [J].

Boddu, Prajwal ;

Gibbons, Jamie ;

Burger, Jan ;

Sivina, Mariela ;

Thakral, Beenu ;

Kanagal-Shamanna, Rashmi ;

Ferrajoli, Alessandra .

LEUKEMIA & LYMPHOMA, 2019, 60 (06) :1568-1571

[4] Secondary Philadelphia chromosome in a patient with acute lymphoblastic leukemia [J].

Chen, L ;

Stamatoullas, A ;

Bastard, C ;

Tilly, H .

CANCER GENETICS AND CYTOGENETICS, 2004, 152 (02) :132-135

[5] Chronic myelogenous leukemia in patients with MPL or JAK2 mutation-positive myeloproliferative neoplasm [J].

Chen, Z. ;

Wang, W. ;

Verstovsek, S. ;

Cortes, J. E. ;

Medeiros, L. J. ;

Hu, S. .

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2015, 37 (06) :E150-E152

[6] Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML [J].

DiNardo, C. D. ;

Tiong, I. S. ;

Quaglieri, A. ;

MacRaild, S. ;

Loghavi, S. ;

Brown, F. C. ;

Thijssen, R. ;

Pomilio, G. ;

Ivey, A. ;

Salmon, J. M. ;

Glytsou, C. ;

Fleming, S. A. ;

Zhang, Q. ;

Ma, H. ;

Patel, K. P. ;

Kornblau, S. M. ;

Xu, Z. ;

Chua, C. C. ;

Chen, Xufeng ;

Blombery, P. ;

Flensburg, C. ;

Cummings, N. ;

Aifantis, I. ;

Kantarjian, H. ;

Huang, D. C. S. ;

Roberts, A. W. ;

Majewski, I. J. ;

Konopleva, M. ;

Wei, A. H. .

BLOOD, 2020, 135 (11) :791-803

[7] Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML [J].

DiNardo, C. D. ;

Stein, E. M. ;

de Botton, S. ;

Roboz, G. J. ;

Altman, J. K. ;

Mims, A. S. ;

Swords, R. ;

Collins, R. H. ;

Mannis, G. N. ;

Pollyea, D. A. ;

Donnellan, W. ;

Fathi, A. T. ;

Pigneux, A. ;

Erba, H. P. ;

Prince, G. T. ;

Stein, A. S. ;

Uy, G. L. ;

Foran, J. M. ;

Traer, E. ;

Stuart, R. K. ;

Arellano, M. L. ;

Slack, J. L. ;

Sekeres, M. A. ;

Willekens, C. ;

Choe, S. ;

Wang, H. ;

Zhang, V. ;

Yen, K. E. ;

Kapsalis, S. M. ;

Yang, H. ;

Dai, D. ;

Fan, B. ;

Goldwasser, M. ;

Liu, H. ;

Agresta, S. ;

Wu, B. ;

Attar, E. C. ;

Tallman, M. S. ;

Stone, R. M. ;

Kantarjian, H. M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (25) :2386-2398

[8] Mutations in AML: prognostic and therapeutic implications [J].

DiNardo, Courtney D. ;

Cortes, Jorge E. .

HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM, 2016, :348-355

[9]

Kasi Pashtoon M, 2016, Leuk Res Rep, V5, P7, DOI 10.1016/j.lrr.2016.01.002

[10] Philadelphia chromosome positive myelodysplastic syndrome and acute myeloid leukemia-retrospective study and review of literature [J].

Keung, YK ;

Beaty, M ;

Powell, BL ;

Molnar, I ;

Buss, D ;

Pettenati, M .

LEUKEMIA RESEARCH, 2004, 28 (06) :579-586

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