Synthesis of isoxazolylpyrrolones by three-component reaction of α-ketoglutaric acid or its diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes

被引：3
作者：
Sakhno, Yana I. [1 ]
Radchenko, Oleksandr V. [1 ]
Muravyova, Elena A. [1 ]
Sirko, Svitlana M. [1 ]
Shishkina, Svitlana V. [1 ,2 ]
Musatov, Vladimir I. [1 ]
Desenko, Sergey M. [1 ,2 ]
Chebanov, Valentyn A. [1 ,2 ]
机构：
[1] Natl Acad Sci Ukraine, Inst Single Crystals, State Sci Inst, Div Chem Funct Mat, 60 Nauky Ave, UA-61072 Kharkiv, Ukraine
[2] Kharkov Natl Univ, Fac Chem, 4 Svobody Sq, UA-61077 Kharkiv, Ukraine
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2021年 / 57卷 / 03期
基金：
新加坡国家研究基金会;
关键词：
3-amino-5-methylisoxazole; alpha-ketoglutaric acid; 1-(5-methylisoxazol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrol-3-yl]acetic acid; multicomponent reaction; ISOXAZOLE; DERIVATIVES;
D O I：
10.1007/s10593-021-02902-w
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[2-Aryl-4-hydroxy-1-(5-methylisoxazol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrol-3-yl]acetic acids and their esters were synthesized by the three-component reaction of alpha-ketoglutaric acid or its diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes.
引用
收藏
页码：261 / 265
页数：5
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