Few-Layer Graphdiyne Nanosheets Applied for Multiplexed Real-Time DNA Detection

被引：213

作者：

Parvin, Nargish ^{[1
]}

Jin, Quan ^{[1
]}

Wei, Yanze ^{[2
]}

Yu, Ranbo ^{[2
]}

Zheng, Bing ^{[3
]}

Huang, Ling ^{[3
]}

Zhang, Ying ^{[4
]}

Wang, Lianhui ^{[4
]}

Zhang, Hua ^{[5
]}

Gao, Mingyuan ^{[6
]}

Zhao, Huijun ^{[7
]}

Hu, Wenping ^{[8
,9
]}

Li, Yuliang ^{[6
]}

Wang, Dan ^{[1
,7
]}

机构：

[1] Chinese Acad Sci, Inst Proc Engn, CAS Ctr Excellence Nanosci, State Key Lab Biochem Engn, 1 Beiertiao, Beijing 100190, Peoples R China

[2] Univ Sci & Technol Beijing, Sch Met & Ecol Engn, Dept Phys Chem, 30 Xueyuan Rd, Beijing 100083, Peoples R China

[3] Nanjing Tech Univ, Inst Adv Mat, Chem Engn Block,5 Xinmofan Rd, Nanjing 210009, Jiangsu, Peoples R China

[4] Nanjing Univ Posts & Telecommun, Sch Mat Sci & Engn, 9 Wenyuan Rd, Nanjing 210046, Jiangsu, Peoples R China

[5] Nanyang Technol Univ, Sch Mat Sci & Engn, Ctr Programmable Mat, 50 Nanyang Ave, Singapore 639798, Singapore

[6] Chinese Acad Sci, Inst Chem, Zhongguancun North First St 2, Beijing 100190, Peoples R China

[7] Griffith Univ, Ctr Clean Environm & Energy, Gold Coast Campus, Southport, Qld 4222, Australia

[8] Tianjin Univ, Tianjin Key Lab Mol Optoelect Sci, Dept Chem, Sch Sci, 92 Weijin Rd, Tianjin 300072, Peoples R China

[9] Tianjin Univ, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, 92 Weijin Rd, Tianjin 300072, Peoples R China

来源：

ADVANCED MATERIALS | 2017年 / 29卷 / 18期

基金：

中国国家自然科学基金; 澳大利亚研究理事会;

关键词：

QUENCHED FLUORESCENT OLIGONUCLEOTIDES; ULTRASENSITIVE DETECTION; WS2; NANOSHEET; GRAPHENE; NANOPROBES; CELLS; BIOMOLECULES; FABRICATION; GRAPHYNES; PLATFORM;

D O I：

10.1002/adma.201606755

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Despite recent progress in 2D nanomaterials-based biosensing, it remains challenging to achieve sensitive and high selective detection. This study develops few-layer graphdiyne (GD) nanosheets (NSs) that are used as novel sensing platforms for a variety of fluorophores real-time detection of DNA with low background and high signal-to-noise ratio, which show a distinguished fluorescence quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a few-layer GD NSs-based multiplexed DNA sensor is developed.

引用

页数：7

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