A disposable single-use optical sensor for potassium determination based on neutral ionophore

被引：24

作者：

Capitán-Vallvey, LF ^{[1
]}

Ramos, MDF ^{[1
]}

Al-Natsheh, M ^{[1
]}

机构：

[1] Univ Granada, Dept Analyt Chem, E-18071 Granada, Spain

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2003年 / 88卷 / 02期

关键词：

potassium determination; optical test strip; single-use optical sensor; neutral ionophore; chromoionophore; clinical analysis;

D O I：

10.1016/S0925-4005(02)00327-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A disposable single-use optical sensor to determine potassium based on an ion-exchange mechanism is described. The test strip is formed by a circular sensing film zone 6 mm in diameter and 4.7 mum in thickness that contains all the reagents necessary to produce a selective response to potassium on a polyester sheet. The sensing zone is formed by a plasticised PVC that incorporates the cation-selective neutral ionophore dibenzo-18-crown-6, lipophilised Nile Blue, and a lipophilic salt. At pH 9.0, the absorbance response of the test strip at 660 nm shows a good correlation with the theoretical behavior. All experimental variables that influence response, especially in terms of selectivity and response time, have been studied. The sensor responded linearly in activities in the range of 0.0125 and 76.8 mM. The detection limit is 0.0125 mM, the reproducibility intermembrane, at a medium level of the range, is 3.4%, as R.S.D. of log aK(+) and the intramembrane, 3.0%. The procedure was applied to the determination of potassium in different human plasma samples, pharmaceutical compounds and seawater samples, validating results against a reference procedure. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：217 / 222

页数：6

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