Reference values of clinical chemistry and hematology parameters in rhesus monkeys (Macaca mulatta)

被引：54

作者：

Chen, Younan ^{[1
]}

Qin, Shengfang ^{[1
]}

Ding, Yang ^{[1
]}

Wei, Lingling ^{[1
]}

Zhang, Jie ^{[1
]}

Li, Hongxia ^{[2
]}

Bu, Hong ^{[3
]}

Lu, Yanrong ^{[1
]}

Cheng, Jingqiu ^{[1
]}

机构：

[1] Sichuan Univ, Key Lab Transplant Engn & Immunol, Minist Hlth, W China Hosp, Chengdu 610041, Sichuan Prov, Peoples R China

[2] Sichuan Univ, W China Hosp, Natl Ctr Safety Evaluat Tradit Chinese Med, Chengdu 610041, Sichuan Prov, Peoples R China

[3] Sichuan Univ, W China Hosp, Dept Pathol, Chengdu 610041, Sichuan Prov, Peoples R China

来源：

XENOTRANSPLANTATION | 2009年 / 16卷 / 06期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

chemistry; coagulation; hematology; reference values; rhesus monkey;

D O I：

10.1111/j.1399-3089.2009.00554.x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Background: Rhesus monkey models are valuable to the studies of human biology. Reference values for clinical chemistry and hematology parameters of rhesus monkeys are required for proper data interpretation. Methods: Whole blood was collected from 36 healthy Chinese rhesus monkeys (Macaca mulatta) of either sex, 3 to 5 yr old. Routine chemistry and hematology parameters, and some special coagulation parameters including thromboelastograph and activities of coagulation factors were tested. Results and conclusion: We presented here the baseline values of clinical chemistry and hematology parameters in normal Chinese rhesus monkeys. These data may provide valuable information for veterinarians and investigators using rhesus monkeys in experimental studies.

引用

页码：496 / 501

页数：6

共 6 条

[1] Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques [J].