Water-soluble phosphonium salts containing 1,12-dicarba-closo-dodecaborane(12)

被引：10

作者：

Ioppolo, Joseph A. ^{[1
]}

Kassiou, Michael ^{[1
,2
,3
]}

Rendina, Louis M. ^{[1
]}

机构：

[1] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia

[2] Univ Sydney, Discipline Med Radiat Sci, Sydney, NSW 2006, Australia

[3] Univ Sydney, Brain & Mind Res Inst, Sydney, NSW 2050, Australia

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 47期

基金：

澳大利亚研究理事会;

关键词：

Phosphonium salt; Carborane; Ethylene glycol; Hydrophilic; BNCT; NEUTRON-CAPTURE THERAPY; DELOCALIZED LIPOPHILIC CATIONS; IN-VITRO EVALUATION; CAGE DEGRADATION; CARCINOMA-CELLS; AMINO-ACIDS; P-CARBORANE; CYTOTOXICITY; DERIVATIVES; MITOCHONDRIA;

D O I：

10.1016/j.tetlet.2009.08.112

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of new water-soluble phosphonium salts containing 1,12-dodeca-closo-dodecaborane(12) (closo-1,12-carborane) for potential use as tumor-targeting agents in Boron Neutron Capture Therapy (BNCT) is described (C) 2009 Elsevier Ltd All rights reserved

引用

页码：6457 / 6461

页数：5

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