Novel 12-deoxy-16-hydroxyphorbol diesters isolated from the seed oil of Jatropha curcas

被引：131

作者：

Haas, W ^{[1
]}

Sterk, H ^{[1
]}

Mittelbach, M ^{[1
]}

机构：

[1] Karl Franzens Univ Graz, Inst Chem, A-8010 Graz, Austria

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 10期

关键词：

D O I：

10.1021/np020060d

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six unstable intramolecular diterpene esters were isolated from the seed oil of Jatropha curcas. Five of these, Jatropha factors C-2-C-6 (3-7), are new natural products and the structure of the known Jatropha factor C-1 (2) has,been revised. All compounds possess the same diterpene moiety, namely, 12-deoxy-16-hydroxyphorbol (1). The dicarboxylic acid moieties of 2-5 contain a bicyclo[3.1.0]hexane unit, and those of 6 and 7 a cyclobutane unit, which is described for the first time within this compound class. Compounds 4 and 5 are C-8' epimers. The structures of 2-7 were elucidated by spectroscopic methods and give an insight into the biogenesis of the characterized substances.

引用

页码：1434 / 1440

页数：7

共 33 条

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